New ellagitannins from Tiencha and their inhibitory activity against dental plaque

By Fusako Nakano, Shozo Miyoshi, Toshiyuki Murakami

August 13, 2018

  • Year

  • Technique

  • Industry

Title

New ellagitannins from Tiencha and their inhibitory activity against dental plaque

Author

Fusako Nakano, Shozo Miyoshi, Toshiyuki Murakami

Year

2017

Journal

Journal of Natural Medicines

Abstract

Four new galloyl-oxygen-diphenyl (GOD)-type ellagitannins, brambliins A–D (1–4), were isolated from the leaves of Rubus suavissimus. Their structures were elucidated by extensive spectroscopic analyses and the absolute configurations of 1–4 were determined by chemical and phytochemical evidence. These GOD-type ellagitannins inhibited the formation of dental plaque, which is beneficial for oral hygiene.

Full Article

https://link.springer.com/article/10.1007/s11418-017-1090-9

Instrument

J-1500

Keywords

Circular dichroism, Stereochemistry, Cotton effect, Natural products, Medicinal, Pharmaceutical