56 articles for the search > coronavirus
2020 / Scientific Reports
The yeast Pichia pastoris is a cost-effective and easily scalable system for recombinant protein production. In this work we compared… Continue reading Structural and functional comparison of SARS-CoV-2-spike receptor binding domain produced in Pichia pastoris and mammalian cells
2005 / Proteomics
Severe acute respiratory syndrome (SARS) is a serious health threat and its early diagnosis is important for infection control and… Continue reading Biochemical and immunological studies of nucleocapsid proteins of severe acute respiratory syndrome and 229E human coronaviruses
2016 / Journal of Virology
The fusion peptides (FP) play an essential role in fusion of viral envelope with cellular membranes. The location and properties… Continue reading Identification of the Fusion Peptide-Containing Region in Betacoronavirus Spike Glycoproteins
2020 / Chemical Physics Letters 758 (2020) 137935
Treatment for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus that causes Covid-19, may well be predicated on knowledge… Continue reading Computed optical spectra of SARS-CoV-2 proteins
2022 / Mol. Pharmaceutics 2022, 19, 7, 2022–2031
Preservation of the integrity of macromolecular higher-order structure is a tenet central to achieving biologic drug and vaccine product stability… Continue reading A Biopharmaceutical Perspective on Higher-Order Structure and Thermal Stability of mRNA Vaccines
2023 / NPG Asia Materials
To efficiently combat viral infectious diseases, it is important to develop broadly applicable countermeasures, and efficient antiviral systems can be… Continue reading Photoactive Conjugated Polymer-Based Strategy to Effectively Inactivate RNA Viruses
2022 / Nature Chemical Biology
Protein tertiary structure mimetics are valuable tools to target large protein–protein interaction interfaces. Here, we demonstrate a strategy for designing… Continue reading A dimeric proteomimetic prevents SARS-CoV-2 infection by dimerizing the spike protein
2023 / Archiv Der Pharmazie
The endemicity of the pandemic coronavirus disease 2019 (COVID-19) infection proved to be transitional only. Spikes are forming again in… Continue reading Zinc(II) Complexation Strategy for Ultra-Sensitive Fluorimetric Estimation of Molnupiravir: Applications and Greenness Evaluation
2021 / Chemistry A European Journal
Given the emergence of the severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2), which particularly threatens older people with comorbidities such as diabetes… Continue reading Modulation of the Conformational Space of SARS-CoV-2 RNA Quadruplex RG-1 by Cellular Components and the Amyloidogenic Peptides α-Synuclein and hIAPP
2021 / Scientific Reports
The coronavirus pandemic, which appeared in Wuhan, China, in December 2019, rapidly spread all over the world in only a… Continue reading A simple and fast spectroscopy-based technique for Covid-19 diagnosis
2021 / Scientific Report
The maturation of coronavirus SARS-CoV-2, which is the etiological agent at the origin of the COVID-19 pandemic, requires a main… Continue reading The dimer-monomer equilibrium of SARS-CoV-2 main protease is affected by small molecule inhibitors
2021 / Communication Biology
The macro domain is an ADP-ribose (ADPR) binding module, which is considered to act as a sensor to recognize nicotinamide… Continue reading Elucidating the tunability of binding behavior for the MERS-CoV macro domain with NAD metabolites
2021 / Communication Biology
In light of the recent accumulated knowledge on SARS-CoV-2 and its mode of human cells invasion, the binding of viral… Continue reading Human ACE2 peptide-mimics block SARS-CoV-2 pulmonary cells infection
2007 / Human Vaccines
Respiratory syncytial virus (RSV) is the leading cause of severe respiratory infection inchildren worldwide. Recombinant live attenuated viral preparations are… Continue reading High-throughput screening of stabilizers for Respiratory Syncytial Virus: Identification of stabilizers and their effects on the conformational thermostability of viral particles
2015 / Applied and Environmental Microbiology
Loss of ordered molecular structure in proteins is known to increase their adhesion to surfaces. The aim of this work… Continue reading Stability of Secondary and Tertiary Structures of Virus-Like Particles Representing Noroviruses: Effects of pH, Ionic Strength, and Temperature and Implications for Adhesion to Surfaces
2017 / Journal of Pharmaceutical Sciences
From 2002 to 2003, a global pandemic of severe acute respiratory syndrome (SARS) spread to five continents and caused 8,000… Continue reading Optimization of the production process and characterization of the yeast-expressed SARS-CoV recombinant receptor-binding domain (RBD219-N1), a SARS vaccine candidate
