Caveolae are plasma membrane invaginations involved in transport, signalling and mechanical membrane sensing in metazoans. Their formation depends upon multiple… Continue reading A variable undecad repeat domain in cavin1 regulates caveola formation and stability
Leah Pandiscia, PhD
August 13, 2018
Enzyme-catalysed hydrolysis of the inherently chiral aryl acetate rac-11 bearing the bowl-shaped tribenzotriquinacene (TBTQ) core enables the stereoselective synthesis of the enantiomerically… Continue reading Stereoselective synthesis of enantiomerically pure bowl-shaped hydroxytribenzotriquinacenes
Leah Pandiscia, PhD
August 13, 2018
Heavy metal ions and those of aluminum may interact with amyloid-β peptides (Αβ) associated with Alzheimer’s disease, contributing to Aβ… Continue reading Interaction of Amyloid Aβ(9–16) Peptide Fragment with Metal Ions: CD, FT-IR, and Fluorescence Spectroscopic Studies
Leah Pandiscia, PhD
August 13, 2018
Building nanostructured active materials and rational porous structures in air-filters will be significant; to realize high filtration efficiency and low… Continue reading A Nano-Protein Functionalized Hierarchical Composite Air-filter
Leah Pandiscia, PhD
August 13, 2018
Leah Pandiscia, PhD
August 13, 2018
Lactic acid enantiomers, normally found in fermented food, are absorbed into the blood and interact with plasma carrier protein human… Continue reading Stereoselective interactions of lactic acid enantiomers with HSA: Spectroscopy and docking application
Leah Pandiscia, PhD
August 13, 2018
Leah Pandiscia, PhD
August 13, 2018
Bombyx mori-derived silk fibroin (SF) is a well-characterized protein employed in numerous biomedical applications. Structurally, SF consists of a heavy… Continue reading The interplay between silk fibroin’s structure and its adhesive properties
Leah Pandiscia, PhD
August 13, 2018
Understanding the impacts of the internal cohesion and surface chemistry of supramolecular systems on the collective behaviors in the contacts… Continue reading Functional Control of Peptide Amphiphile Assemblies via Modulating Internal Cohesion and Surface Chemistry Switch
Leah Pandiscia, PhD
August 13, 2018
Chiral inversion of single molecules has been a challenging task because chirality information controls structures and func-tions of various molecules,… Continue reading pseudo[1]Catenane-Type Pillar[5]thiacrown Whose Planar Chiral Inversion is Triggered by Metal Cation and Controlled by Anion
Leah Pandiscia, PhD
August 13, 2018
This work reports the synthesis of bare and surface modified titanium dioxide nanoparticles (TiO2 NPs) via solvothermal decomposition using titanium isopropoxide as the… Continue reading Synthesis of bare and surface modified TiO2 nanoparticles via a single source precursor and insights into their interactions with serum albumin
Leah Pandiscia, PhD
August 13, 2018
The Chinese Xi-Gui tea is one ancient cultivated variety of Camellia sinensis var. assamica. It has been used for producing… Continue reading Flavoalkaloids with Pyrrolidinone Ring from Chinese Ancient Cultivated Tea Xi-Gui
Leah Pandiscia, PhD
August 13, 2018
A colorimetric method is presented for the determination of the antibiotic ofloxacin (OFL) in aqueous solution. It is based on… Continue reading Colorimetric determination of ofloxacin using unmodified aptamers and the aggregation of gold nanoparticles
Leah Pandiscia, PhD
August 13, 2018
Intrinsically disordered regions (IDRs) of proteins often regulate function through interactions with folded domains. Escherichia coli single-stranded DNA binding protein SSB binds… Continue reading Escherichia coli AlkB interacts with single-stranded DNA binding protein SSB by an intrinsically disordered region of SSB
Leah Pandiscia, PhD
August 13, 2018
Protein binding specificities can be manipulated by redesigning contacts that already exist at an interface or by expanding the interface… Continue reading Engineering a Protein Binder Specific for p38α with Interface Expansion
Leah Pandiscia, PhD
August 13, 2018
Dye effluents are one of main sources of concern causing water pollution. Azo dyes, most widely applied colorants, are particularly… Continue reading Calorimetric and Spectroscopic Detection of Interaction Between a Diazo Dye and Human Serum Albumin
Leah Pandiscia, PhD
August 13, 2018
Here we report on covalently immobilized poly(ethyl acrylate-co-methacrylic acid) microgels loaded with the host defense peptide KYE28 (KYEITTIHNLFRKLTHRLFRRNFGYTLR), which is… Continue reading Peptide-loaded microgels as antimicrobial and anti-inflammatory surface coatings
Leah Pandiscia, PhD
August 13, 2018
Encapsulation of hydrophobic guest molecules inside the micelle and their stimuli-sensitive release is a useful strategy for the target-specific drug… Continue reading Impact of Glycolipids Hydrophobic Chain Length, Headgroup Size on Self-Assembly and Hydrophobic Guest Release
Leah Pandiscia, PhD
August 13, 2018
Amyloid fibrils are cross-β-sheet rich protein/peptide fibrils that are typically associated with neurodegenerative diseases such as Parkinson’s and Alzheimer’s disease.… Continue reading Amyloid Fibrils with Positive Charge Enhance Retroviral Transduction in Mammalian Cells
Leah Pandiscia, PhD
August 13, 2018
A new carbon dots (CDs) based nanoprobe for ratiometric fluorescence detection of DNA was constructed in this work. Thiazole orange… Continue reading Thiazole orange modified carbon dots for ratiometric fluorescence detection of G-quadruplex and double-stranded DNA
Leah Pandiscia, PhD
August 13, 2018