Found 9617 Results / Page 163 of 481

DMSO strengthens chitin deacetylase-chitin interaction: Physicochemical, kinetic, structural and catalytic insights

2019 / Carbohydrate Polymers

Chitin deacetylase, an enzyme isolated from Cryptococcus laurentii RY1, catalyzes the hydrolysis of acetamido group of N-acetyl-D-glucosamine unit of chitin. The primary objective… Continue reading DMSO strengthens chitin deacetylase-chitin interaction: Physicochemical, kinetic, structural and catalytic insights

Leah Pandiscia, PhD

Magnetic cationic liposomal nanocarriers for the efficient drug delivery of a curcumin-based vanadium complex with anticancer potential

2019 / Journal of Inorganic Biochemistry

In this work novel magnetic cationic liposomal nanoformulations were synthesized for the encapsulation of a crystallographically defined ternary V(IV)-curcumin-bipyridine (VCur)… Continue reading Magnetic cationic liposomal nanocarriers for the efficient drug delivery of a curcumin-based vanadium complex with anticancer potential

Leah Pandiscia, PhD

Nonnucleoside Reverse Transcriptase Inhibitor Hypersusceptibility and Resistance by Mutation of Residue 181 in HIV-1 Reverse Transcriptase

2019 / Antimicrobial Agents and Chemotherapy

Substitutions at residue Y181 in HIV-1 reverse transcriptase (RT), in particular, Y181C, Y181I, and Y181V, are associated with nonnucleoside RT… Continue reading Nonnucleoside Reverse Transcriptase Inhibitor Hypersusceptibility and Resistance by Mutation of Residue 181 in HIV-1 Reverse Transcriptase

Leah Pandiscia, PhD

Light-sensitive dextran-covered PNBA nanoparticles to continuously or discontinuously improve the drug release

2019 / Colloids and Surfaces B: Biointerfaces

In this work, photo-sensitive core/shell nanoparticles (NPs) based on biocompatible dextran-g-poly(o-nitrobenzyl acrylate) copolymers (Dex-g-PNBA), containing dextran as hydrophilic backbone and… Continue reading Light-sensitive dextran-covered PNBA nanoparticles to continuously or discontinuously improve the drug release

Leah Pandiscia, PhD

An investigation on host-guest complexation of Metformin hydrochloride with hydroxypropyl-α-cyclodextrin for enhanced oral bioavailability

2019 / Materials Proceedings: Today

Metformin hydrochloride is an orally administered biguanide which is an oral anti-hyperglycemic agent. It shows incomplete absorption from the gastrointestinal… Continue reading An investigation on host-guest complexation of Metformin hydrochloride with hydroxypropyl-α-cyclodextrin for enhanced oral bioavailability

Leah Pandiscia, PhD

Thermally induced cyclization of L‐isoleucyl‐L‐alanine in solid state: Effect of dipeptide structure on reaction temperature and self‐assembly

2019 / Journal of Peptide Science

Thermal treatment of short‐chain oligopeptides is able to initiate the process of their self‐assembly with the formation of organic nanostructures… Continue reading Thermally induced cyclization of L‐isoleucyl‐L‐alanine in solid state: Effect of dipeptide structure on reaction temperature and self‐assembly

Leah Pandiscia, PhD

Combined Transition-Metal/Enzyme Dual Catalytic System for Highly Intensive Glow-Type Chemiluminescence-Functionalized CaCO3 Microspheres

2019 / Analytical Chemistry

Chemiluminescent (CL) reagent N-(4-aminobutyl)-N-ethylisoluminol (ABEI)-functionalized CaCO3 microspheres with a dual catalytic system consisting of Co2+ and horseradish peroxidase (HRP) (HRP/ABEI/Co2+-CaCO3 MPs) were synthesized via… Continue reading Combined Transition-Metal/Enzyme Dual Catalytic System for Highly Intensive Glow-Type Chemiluminescence-Functionalized CaCO3 Microspheres

Leah Pandiscia, PhD
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