Leah Pandiscia, PhD
September 22, 2019
Carlos Morillo
September 17, 2019
Carbonic anhydrase (CA) IX overexpresses exclusively on cell membranes of hypoxic tumors, regulating the acidic tumor microenvironment. Small molecules of… Continue reading New power of self-assembling carbonic anhydrase inhibitor: Short peptide–constructed nanofibers inspire hypoxic cancer therapy
Heather Haffner
September 13, 2019
A synthesis of chiral hydrocarbons having C1 axis and C3 symmetry, which owe their chirality due to asymmetrical distribution of… Continue reading Asymmetric Synthesis and Stereochemical Assignment of 12C/13C Isotopomers
Carlos Morillo
September 11, 2019
Leah Pandiscia, PhD
July 30, 2019
The enantioselective electrophilic fluorination of α-aryl-tetralones is promoted by cinchonine/selectfluor combinations. This strategy allows a facile synthesis of the corresponding… Continue reading Enantioselective electrophilic fluorination of α-aryl-tetralones using a
preparation of N-fluoroammonium salts of cinchonine
Leah Pandiscia, PhD
July 30, 2019
It has been generally recognized that chiral inorganic materials can be efficiently fabricated via a templated-synthesis route in the presence of chiral… Continue reading Chiroptical phenolic resins grown on chiral silica-bonded amine residues
Leah Pandiscia, PhD
July 30, 2019
Leah Pandiscia, PhD
July 30, 2019
The enantiomers of a homologous series (C6–C10) of 2-mercapto-4-alkanones were obtained by lipase-catalyzed kinetic resolution of the corresponding racemic 2-acetylthio-4-alkanones.… Continue reading Determination of the Absolute Configurations and Sensory Properties of the Enantiomers of a Homologous Series (C6–C10) of 2-Mercapto-4-alkanones
Leah Pandiscia, PhD
July 30, 2019
The VCD spectra of several chiral compounds containing the CF3 group are reviewed and analyzed. The list of compounds contains pharmaceutically… Continue reading CF3: an overlooked chromophore in VCD spectra. A review of recent applications in structural determination
Leah Pandiscia, PhD
July 30, 2019
Leah Pandiscia, PhD
July 30, 2019
Leah Pandiscia, PhD
July 30, 2019
The interest of circular dichroism in the solid state is stimulated by sev-eral needs, such as the desire to get… Continue reading Experimental Aspects of Solid State Circular Dichroism
Leah Pandiscia, PhD
July 30, 2019
Apomorphine is a chiral drug molecule; notwithstanding its extraordinary importance, little attention has been paid to the characterization of its… Continue reading Electronic and vibrational circular dichroism spectra of (R)-(−)-apomorphine
Leah Pandiscia, PhD
July 30, 2019
The implementation of a strategy comprising the use of vibrational circular dichroism spectroscopy and DFT calculations allows determination of the… Continue reading DFT‐Aided Vibrational Circular Dichroism Spectroscopy Study of (−)‐S‐cotinine
Leah Pandiscia, PhD
July 30, 2019
S-(−)-Perillaldehyde (4-isopropenylcyclohex-1-ene-1-carbaldehyde) is a secondary metabolite and an atmospheric pollutant obtained from the oxidation of other terpenes, as limonene and… Continue reading Conformational Flexibility in Terpenes: Vibrational Circular Dichroism (VCD), Infrared and Raman Study of S-(−)-Perillaldehyde
Leah Pandiscia, PhD
July 30, 2019
Chiral discs: Seemingly flat disc‐like molecules form a columnar phase and spontaneously segregate into macroscopic chiral domains (deracemization). Quantum chemical… Continue reading Spontaneous Deracemization of Disc‐like Molecules in the Columnar Phase
Leah Pandiscia, PhD
July 30, 2019
This paper reports on the polymorphism of 2-propyl-1H-benzimidazole (2PrBzIm) induced by temperature change. Upon heating, an irreversible reconstructive-type phase transition… Continue reading Conformational aspects of polymorphs and phases of 2-propyl-1H-benzimidazole
Leah Pandiscia, PhD
July 30, 2019
(S)-(−)-Perillyc acid (4-isopropenylcyclohexene-1-carboxylic acid) is an intermediate in the limonene and pinene pathway degradation and its measurement in urine is… Continue reading Conformational landscape and hydrogen bonding in (S)-(−)-perillyc acid: experimental VCD, IR, Raman, and theoretical DFT studies
Leah Pandiscia, PhD
July 30, 2019
Leah Pandiscia, PhD
July 30, 2019