In this article, we have reported the exogenous delivery of a newly synthesized biologically relevant fluorophore, namely, (E)-1,5-diphenyl-3-styryl-4,5 -dihydro-1H-pyrazole (DSDP)… Continue reading Exogenous delivery of a pyrazole based bioactive probe to natural DNA through non-ionic TX-165 micellar carrier
Leah Pandiscia, PhD
April 9, 2019
High‐pressure homogenization (HPH) under 0–100 MPa was performed to treat clam protein isolate (CPI) for three cycles. Results indicated that HPH… Continue reading Structure and functionalities changes in high‐pressure homogenized clam protein isolate
Leah Pandiscia, PhD
April 9, 2019
Non-coding RNAs are functional RNA molecules that get transcribed from DNA but are not translated into proteins; yet, they can… Continue reading Restoration of miRNA-149 expression by TmPyP4 induced unfolding of quadruplex within its precursor
Leah Pandiscia, PhD
April 9, 2019
The chimeric peptide HPRP-A1-iRGD, composed of a chemically conjugated tumor homing/penetration domain (iRGD) and a cationic anticancer peptide domain (HPRP-A1),… Continue reading Targeted modification of the cationic anticancer peptide HPRP-A1 with iRGD to improve specificity, penetration, and tumor-tissue accumulation
Leah Pandiscia, PhD
April 9, 2019
The growing area of biomaterial sciences has drawn a broad attention over recent years on the development of peptide-based biocompatible… Continue reading Investigations of Anti-Inflammatory Activity of a Peptide-Based Hydrogel using Rat Air Pouch Model
Leah Pandiscia, PhD
April 9, 2019
Leah Pandiscia, PhD
April 9, 2019
A highly selective circular dichroism sensor based on cysteamine-capped cadmium sulfide quantum dots (Cys-CdS QDs) was successfully developed for the determination of Cu2+.… Continue reading Highly selective circular dichroism sensor based on D-penicillamine/ cysteamine cadmium sulfide quantum dots for copper (II) ion detection
Leah Pandiscia, PhD
April 9, 2019
The photoisomerization of azobenzenes provides a general means for the photocontrol of many important biomolecular structure and organismal function. For… Continue reading Reversible Photocontrol of Thrombin Activity by Replacing Loops of Thrombin Binding Aptamer using Azobenzene Derivatives
Leah Pandiscia, PhD
April 9, 2019
In the current study, the extracellular endopeptidases from Pseudomonas lundensis and Pseudomonas proteolytica were investigated. The amino acid sequence identity… Continue reading Two heat resistant endopeptidases from Pseudomonas species with destabilizing potential during milk storage
Leah Pandiscia, PhD
April 9, 2019
Leah Pandiscia, PhD
April 9, 2019
New efficient catalysts based on electrophilic N‐fluoro quaternary ammonium salts are reported for catalytic allylation of (E)‐N,1‐diphenylmethanimine. The chiral version of… Continue reading Electrophilic [N—F]+ catalysed asymmetric allylation of (E)‐N,1‐diphenylmethanimine
Leah Pandiscia, PhD
April 9, 2019
A series of trans-palladium(II) complexes (trans-[PdCl2L2], L = ethyl 5-R-2H-tetrazol-2-ylacetate, 5-R-2H-tetrazol-2-ylacetamides, R = Me, Ph) has been synthesized, and their structure… Continue reading Synthesis, Structure, and Antiproliferative Activity of trans-Palladium(II) Complexes with Tetrazol-2-ylacetic Acid Derivatives
Leah Pandiscia, PhD
April 9, 2019
Sample configurations of distaminolyne A (1a); isolated from the ascidians Pseudodistoma opacum and P. cereum, and collected at different sites in New Zealand,… Continue reading Enantiomeric Variability of Distaminolyne A. Refinement of ECD and NMR Methods for Determining Optical Purity of 1-Amino-2-Alkanols
Leah Pandiscia, PhD
April 9, 2019
Leah Pandiscia, PhD
April 9, 2019
A peptide comprising the juxtamembrane C‐terminal intracellular loop 4 (IL4) of the CB1cannabinoid receptor possesses three serine residues (Ser402, Ser411,… Continue reading CB1 cannabinoid receptor‐phosphorylated fourth intracellular loop structure‐function relationships
Leah Pandiscia, PhD
April 9, 2019
To achieve desired physicochemical and biochemical activities of optically active molecules at targetted sites in biological systems, tuning of chiral… Continue reading pH-Regulated supramolecular chirality of phenylalanine-based hydrogels
Leah Pandiscia, PhD
April 9, 2019
Proteins with multifunctional regulatory domains often demonstrate structural plasticity or protein disorder, allowing the binding of multiple regulatory factors and… Continue reading Intrinsic disorder in the regulatory N-terminal domain of diacylglycerol acyltransferase 1 from Brassica napus
Leah Pandiscia, PhD
April 9, 2019
Monoclonal antibodies have emerged as an important class of therapeutics in oncological and autoimmune diseases due to their several attractive… Continue reading One-pot stapling of interchain disulfides of antibodies using an isobutylene motif
Leah Pandiscia, PhD
April 9, 2019
Chiral recognition is of fundamental importance in chemistry and life sciences and the principle of chiral recognition is instructive in… Continue reading A Surface Mediated Supramolecular Chiral Phenomenon for Recognition of L-and D-Cysteine
Leah Pandiscia, PhD
April 9, 2019
By investigating of the roots of Salvia miltiorrhiza, which is one of the most widely used Chinese herbs, we used phytochemical… Continue reading Four New Depsides Isolated from Salvia miltiorrhiza and Their Significant Nerve-Protective Activities
Leah Pandiscia, PhD
April 9, 2019