An optically active bithiophene derivative containing a D-glucose residue and two ethynyl groups ((aR)-7) was synthesized and copolymerized with 2,5-diiodothiophene… Continue reading Helicity control of π-conjugated foldamers containing D-glucose-based single enantiomeric units as a chiral source
Leah Pandiscia, PhD
April 8, 2019
Functionalized nanoparticle cross-linked collagen scaffolds offer improved properties to biomaterials and regenerated tissues. As influence of nanoparticle shape on collagen… Continue reading Collagen-ZnO scaffolds for wound healing applications: Role of dendrimer functionalization and nanoparticle morphology
Leah Pandiscia, PhD
April 8, 2019
Human sialic acid-binding immunoglobulin-like lectin 14 (Siglec-14) is a glycan-recognition protein that is expressed on myeloid cells, recognizes bacterial pathogens,… Continue reading Soluble Siglec-14 glycan-recognition protein is generated by alternative splicing and suppresses myeloid inflammatory responses
Leah Pandiscia, PhD
April 8, 2019
Transdermal immunization is highly attractive owing to the skin accessibility and unique immunological character. However, it remains a relatively unexplored… Continue reading Effect of Delivery Platforms Structure on the Epidermal Antigen Transport for Topical Vaccination
Leah Pandiscia, PhD
April 8, 2019
Altering the cultivation conditions, such as temperature, media compositions, illumination, aeration, the shape of the culturing flask, etc., was regarded… Continue reading Anti-inflammatory fusicoccane-type diterpenoids from the phytopathogenic fungus Alternaria brassicicola
Leah Pandiscia, PhD
April 8, 2019
Lipid-modification of proteins plays a significant role in regulating the cellular environment. Mimicking natural lipidated proteins is a key technique… Continue reading Design of Lipid-Protein Conjugates Using Amphiphilic Peptide Substrates of Microbial Transglutaminase
Leah Pandiscia, PhD
April 8, 2019
The structure of the known Penicillium aurantiogriseum-derived secondary metabolite auranthine was refined using a combination of synthetic, spectroscopic, and X-ray diffractometric… Continue reading Auranthine, a Benzodiazepinone from Penicillium aurantiogriseum: Refined Structure, Absolute Configuration, and Cytotoxicity
Leah Pandiscia, PhD
April 8, 2019
The nanomaterial composition of nanoparticles and their protein adsorption in the blood is of great significance in the design of… Continue reading Pullulan-Based Nanoparticle-HSA Complex Formation and Drug Release Influenced by Surface Charge
Leah Pandiscia, PhD
April 8, 2019
We compared the synthesis and structural/conformational details of the (66–97) segments of the second transmembrane helix of AT1, MAS and… Continue reading Major G-Quadruplex Form of HIV-1 LTR Reveals a (3 + 1) Folding Topology Containing a Stem-Loop
Leah Pandiscia, PhD
April 8, 2019
Leah Pandiscia, PhD
April 8, 2019
In coiled-coil (CC) protein structures α-helices wrap around one another to form rope-like assemblies. Most natural and designed CCs have… Continue reading Maintaining and breaking symmetry in homomeric coiled-coil assemblies
Leah Pandiscia, PhD
April 8, 2019
Circularly polarized luminescence (CPL) from well-organized structures of aggregates has been intensely investigated, while rational design of π-conjugated polymers with… Continue reading Control of circularly polarized luminescence from a boron ketoiminate-based π-conjugated polymer via conformational locks
Leah Pandiscia, PhD
April 8, 2019
New boranils based on chiral benzylamines have been synthesized and their photophysical properties studied. These BF2-complexes exhibit a bright blue… Continue reading Aggregation-induced emission enhancement of chiral boranils
Leah Pandiscia, PhD
April 8, 2019
Protein glycation via the Maillard reaction is widely used to modify the functional properties of proteins. Using four explored reaction conditions, two maltose-glycated caseinate… Continue reading Structure and property changes of the maltose-glycated caseinate prepared through the Maillard reaction in an ionic liquid medium
Leah Pandiscia, PhD
April 8, 2019
Leah Pandiscia, PhD
April 8, 2019
Leah Pandiscia, PhD
April 8, 2019
Triplex molecular beacons (tMBs) possess great potential in biological sensing because of the pH responsiveness and controllability of binding strength.… Continue reading Classical Triplex Molecular Beacons for MicroRNA-21 and Vascular Endothelial Growth Factor Detection
Leah Pandiscia, PhD
April 8, 2019
Catechins, polyphenols derived from tea leaves, have been shown to have antibacterial properties, through direct killing of bacteria as well… Continue reading Catechin-mediated restructuring of a bacterial toxin inhibits activity
Leah Pandiscia, PhD
April 8, 2019
The peptide hormone glucagon, used to treat hypoglycaemic incidents, is prone to aggregation. Generating alternatives with better stability is of… Continue reading The Use of Surfactants to Solubilise a Glucagon Analogue
Leah Pandiscia, PhD
April 8, 2019
G-quadruplexes occur in promoter regions, 5′-untranslated regions of mRNA and telomeric regions, and they function as regulatory elements for various… Continue reading Transcription Driven by Reversible Photocontrol of Hyperstable G-Quadruplexes
Leah Pandiscia, PhD
April 8, 2019