Small heat-shock proteins (sHsps) are ubiquitous molecular chaperones, and their mutations or altered expression are linked to multiple human disease… Continue reading It takes a dimer to tango: Oligomeric small heat-shock proteins dissociate to capture substrate
Leah Pandiscia, PhD
August 13, 2018
Phosphine gold(I) aryl acetylide complexes equipped with a central bis(urea) moiety form 1D hydrogen‐bonded polymeric assemblies in solution that do… Continue reading Induced Circular Dichroism in Phosphine Gold(I) Aryl Acetylide Urea Complexes through Hydrogen‐Bonded Chiral Co‐Assemblies
Leah Pandiscia, PhD
August 13, 2018
Among the protein folding motifs, which are accessible by de novo design, the parallel heterodimeric coiled coil is most frequently used in… Continue reading Kinetic studies on strand displacement in de novo designed parallel heterodimeric coiled coils
Leah Pandiscia, PhD
August 13, 2018
FeS-clusters are utilized by numerous proteins within several biological pathways that are essential for life. In eukaryotes, the primary FeS-cluster… Continue reading In vitro characterization of a novel Isu homologue from Drosophila melanogaster for de novo FeS-cluster formation
Leah Pandiscia, PhD
August 13, 2018
Kinetoplastid membrane protein-11 (KMP11) is a membrane-associated surface protein of kinetoplastids, which has a strong antigenicity but no mammalian homolog,… Continue reading Kinetoplastid membrane protein‐11 adopts a four‐helix bundle fold in DPC micelle
Leah Pandiscia, PhD
August 13, 2018
Apolipoprotein A-I (apoA-I) undergoes a large conformational reorganization during remodeling of high-density lipoprotein (HDL) particles. To detect structural transition of… Continue reading Immunochemical Approach for Monitoring of Structural Transition of ApoA-I upon HDL Formation Using Novel Monoclonal Antibodies
Leah Pandiscia, PhD
August 13, 2018
In this article, a chiral plasmonic hydrogen‐sensing platform using palladium‐based nanohelices is demonstrated. Such 3D chiral nanostructures fabricated by nanoglancing… Continue reading Chiral Plasmonic Hydrogen Sensors
Leah Pandiscia, PhD
August 13, 2018
Leah Pandiscia, PhD
August 13, 2018
Leah Pandiscia, PhD
August 13, 2018
Sodium deoxycholate modified silver nanoparticles prepared in the presence of sodium deoxycholate as a chiral inducer exhibit plasmonic circular dichroism… Continue reading Synthesis and Plasmonic Chiroptical Studies of Sodium Deoxycholate Modified Silver Nanoparticles
Leah Pandiscia, PhD
August 13, 2018
The role of Ca2+ in gelation of myosin extracted from silver carp (Hypophthalmichthys molitrix) was investigated. Compared with the control, myosin… Continue reading Ca2+-Induced Conformational Changes of Myosin from Silver Carp (Hypophthalmichthys molitrix) in Gelation
Leah Pandiscia, PhD
August 13, 2018
Peptides and proteins represent a promissory group of molecules used by the pharmaceutical industry for drug therapy with great potential… Continue reading Inkjet Printing of Proteins: an Experimental Approach
Leah Pandiscia, PhD
August 13, 2018
To produce high-quality surimi, we investigated the effect of ozone-induced mild oxidation on structural changes of silver carp myosin by… Continue reading Effect of Mild Ozone Oxidation on Structural Changes of Silver Carp (Hypophthalmichthys molitrix) Myosin
Leah Pandiscia, PhD
August 13, 2018
Two pairs of new enantiomers with unusual 5,5-spiroketal cores, termed (±)-japonones A and B [(±)-1 and (±)-2], were obtained from Hypericum japonicum Thunb.… Continue reading (±)-Japonones A and B, two pairs of new enantiomers with anti-KSHV activities from Hypericum japonicum
Leah Pandiscia, PhD
August 13, 2018
Artificial metalloenzymes (ArMs) formed by incorporating synthetic metal catalysts into protein scaffolds have the potential to impart to chemical reactions… Continue reading Engineering a dirhodium artificial metalloenzyme for selective olefin cyclopropanation
Leah Pandiscia, PhD
August 13, 2018
Leah Pandiscia, PhD
August 13, 2018
We determined the crystal structure of EcL‐DER to elucidate protein function and substrate specificity. Unlike other asp/glu racemases, EcL‐DER has an unbalanced… Continue reading Structural basis for an atypical active site of an l‐aspartate/glutamate‐specific racemase from Escherichia coli
Leah Pandiscia, PhD
August 13, 2018
A metal‐coordinated α‐helical peptide monolayer shows exceptional vectorial electron transfer. It also displays rectification behavior whereby an alternating current signal is… Continue reading Piezoelectric‐Enhanced Oriented Cobalt Coordinated Peptide Monolayer with Rectification Behavior
Leah Pandiscia, PhD
August 13, 2018
Cytochrome c is an essential mediator of apoptosis when it is released from the mitochondria to the cytoplasm. This process… Continue reading Activation of caspase-dependent apoptosis by intracellular delivery of cytochrome c-based nanoparticles
Leah Pandiscia, PhD
August 13, 2018
Magneto optical devices based on the Faraday effects of lanthanide ion have attracted much attention. Recently, large Faraday effects were… Continue reading Molecular Design Guidelines for Large Magnetic Circular Dichroism Intensities in Lanthanide Complexes
Leah Pandiscia, PhD
August 13, 2018