Catalysis without a headache: Modification of ibuprofen for the design of artificial metalloenzyme for sulfide oxidation
Laurianne Rondot, Elodie Girgenti, Frédéric Oddon, Caroline Marchi-Delapierre, Adeline Jorge-Robin, Stéphane Ménage
Journal of Molecular Catalysis A: Chemical
A new artificial oxidase has been developed for selective transformation of thioanisole. The catalytic activity of an iron inorganic complex, FeLibu, embedded in a transport protein NikA has been investigated in aqueous media. High efficiency (up to 1367 t), frequency 459 TON min−1 and selectivity (up to 69%) make this easy to use catalytic system an asset for a sustainable chemistry.
Circular dichroism, Stereochemistry, Ligand binding