Circular dichroism and circularly polarised luminescence of bipyrenyl oligopeptides, with piperidines added in the peptide chains

October 11, 2018

Title

Circular dichroism and circularly polarised luminescence of bipyrenyl oligopeptides, with piperidines added in the peptide chains

Author

Yuki Mimura, Sayaka Kitamura, Motohiro Shizuma, Mizuki Kitamatsu, Yoshitane Imai

Year

2018

Journal

Organic & Biomolecular Chemistry

Abstract

Upon combining chiral peptides (the most basic chiral source) with pyrene moieties, we found that chiral oligopeptides bearing two-pendant pyrenyl units exhibited circularly polarised luminescence (CPL) originating from intramolecular excimers at 450–490 nm in various solvents, and the sign of their CPL signals depended on the type of solvent employed. The CPL and circular dichroism signs and intensities could be tuned by the introduction of a piperidine unit into the chiral peptide chain; thus, the obtained structure could be considered a practical Lock ON–OFF system for oligopeptide luminophores.

Instrument

J-820

Keywords

Circular dichroism, Stereochemistry, Chemical stability, Biochemistry