João Grosso Pacheco, Inês Maria Valente, Luís Moreira Gonçalves, José António Rodrigues, Aquiles Araújo Barros
Journal of Separation Science
Gas‐diffusion microextraction (GDME) is an innovative technique that combines the advantages of membrane‐aided gas‐diffusion with microextraction concepts. GDME makes uses of a novel portable and low‐cost device that comprises a small, commercially available, semi‐permeable membrane. Furthermore, if derivatization is integrated into the GDME concept, considerable enrichment factors can be obtained. It may become a powerful tool for any analyst who intends to quantify volatile and semi‐volatile analytes in various kinds of matrices. The analysis of vicinal diketones in beer was used as a case study to show GDME applicability and capabilities. Vicinal diketones were derivatized with o‐phenylenediamine and then determined by HPLC‐UV. Obtained results showed good repeatability and precision with extraction periods at the minute time span.
HPLC, Gas-diffusion microextraction, beer, vicinal diketones, o-phenylenediamine