“On–off–on” pyrene‐based fluorescent chemosensor for the selective recognition of Cu2+ and S2− ions and its utilization in live cell imaging
Dhivya Rajasekaran, Kavitha Venkatachalam, Viswanathamurthi Periasamy
Applied Organometallic Chemistry
A new “on–off–on” fluorescence chemosensor (DPD) was designed, synthesized, and characterized based on pyrene and benzothiozole hydrazide. The probe DPD shows high affinity towards Cu2+ ions and the DPD‐Cu2+ ensemble shows high sensitivity towards S2− ions through the displacement method in the presence of other interfering ions. The detection limits of DPD for Cu2+ and S2− ions were found to be 0.73 and 0.87 nM, respectively. Furthermore, the receptor was effectively applied to recognize Cu2+ and S2− ions in real samples and live A549 cells through imaging studies.
Fluorescence, Ligand binding, Sensors, Quantitation, Materials