Tuning Liposome Membrane Permeability by Competitive Peptide Dimerization and Partitioning-Folding Interactions Regulated by Proteolytic Activity

2016 / Scientific Reports

Membrane active peptides are of large interest for development of drug delivery vehicles and therapeutics for treatment of multiple drug …

Leah Pandiscia, PhD

Peroxiredoxin 6 homodimerization and heterodimerization with glutathione S-transferase pi are required for its peroxidase but not phospholipase A2 activity

2016 / Free Radical Biology and Medicine

Peroxiredoxin 6 (Prdx6) is a unique 1-Cys member of the peroxiredoxin family with both GSH peroxidase and phospholipase A2 (PLA2) activities. …

Leah Pandiscia, PhD

Immune indices and identical functions of two prophenoloxidases from the haemolymph of green tiger shrimpPenaeus semisulcatus and its antibiofilm activity

2016 / Fish and Shellfish Immunology

In the present study, we purified two prophenoloxidases (proPO) from haemolymph of green tiger shrimp, Penaeus semisulcatus by gel fermentation chromatography using …

Leah Pandiscia, PhD

The Truncated Human Telomeric Sequence forms a Hybrid-Type Intramolecular Mixed Parallel/antiparallel G-quadruplex Structure in K+Solution

2016 / Chemical Biology and Drug Design

In 80–90% tumor cells, telomerase becomes active and stabilizes the length of telomeres. The formation and stabilization of G-quadruplexes formed …

Leah Pandiscia, PhD