Comparison of two phenotypically distinct lattice corneal dystrophies caused by mutations in the transforming growth factor beta induced (TGFBI) gene

2014 / PROTEOMICS - Clinical Applications

In this study, we investigated whether the phenotypic difference observed between two lattice corneal dystrophy type 1 (LCD type 1) …

Leah Pandiscia, PhD

Four new compounds from Ligularia virgaurea: isolation of eremophilane and noreremophilane sesquiterpenoids and the absolute configuration of 2α-hydroxyeremophil-11-en-9-one by CD spectrum and DFT calculation

2013 / Tetrahedron

Four new compounds, rearranged noreremophilan-8,6-olide, rearranged dinoreremophilanone, epoxy γ-lactone, and 2α-hydroxyermophil-11-en-9-one, along with eremophilenolides related to ligularol and other known …

Leah Pandiscia, PhD

5-Hydroxymethyl-2′-Deoxyuridine Residues in the Thrombin Binding Aptamer: Investigating Anticoagulant Activity by Making a Tiny Chemical Modification

2014 / ChemBioChem

We report an investigation into analogues of the thrombin binding aptamer (TBA). Individual thymidines were replaced by the unusual residue …

Leah Pandiscia, PhD

Agarose functionalization: Synthesis of PEG-agarose amino acid nano-conjugate – its structural ramifications and interactions with BSA in a varying pH regime

2016 / Carbohydrate Polymers

In a rapid one-step method protein-mimicking large agarose amino acid framework (AAE; GPC 156.7 kDa) was conjugated with polyethylene glycol (PEG …

Leah Pandiscia, PhD

Colloidal chirality in wormlike micellar systems exclusively originated from achiral species: Role of secondary assembly and stimulus responsivity

2016 / Journal of Colloid and Interface Science

Colloidal chirality in wormlike micellar systems exclusively originated from achiral species and discussion of the role of secondary assembly of …

Leah Pandiscia, PhD

The antimicrobial efficacy and DNA binding activity of the copper(II) complexes of 3,4,7,8-tetramethyl-1,10-phenanthroline, 4,7-diphenyl-1,10-phenanthroline and 1,2-diaminocyclohexane

2016 / Journal of Inorganic Biochemistry

Four copper(II) complexes of the general structure [Cu(L1)(L2)]2 +, where L1 is (1S,2S)-diaminocyclohexane or (1R,2R)-diaminocyclohexane and L2 is 3,4,7,8-tetramethyl-1,10-phenanthroline (TMP) or 4,7-diphenyl-1,10-phenanthroline (DIP), …

Leah Pandiscia, PhD

Studies on the interaction between promethazine and human serum albumin in the presence of flavonoids by spectroscopic and molecular modeling techniques

2016 / Colloids and Surfaces B: Biointerfaces

Fluorescence, absorption, time-correlated single photon counting (TCSPC), and circular dichroism (CD) spectroscopic techniques as well as molecular modeling method were …

Leah Pandiscia, PhD

Binding nature and conformational alternations of bovine serum albumin upon interaction with synthesized LaF3:Ce,Tb luminescent nanocrystals using multi-spectroscopic approach

2016 / Journal of Luminescence

Water-soluble LaF3:Ce,Tb luminescent nanocrystals (RLNCs) were successfully fabricated according to previously reported literatures. The experimental results indicate that the as-prepared …

Leah Pandiscia, PhD

α-Glucosidase Inhibitors via Green Pathway: Biotransformation for Bicoumarins Catalyzed by Momordica charantia Peroxidase

2013 / Journal of Agricultural and Food Chemistry

Peroxidase extracted from Momordica charantia catalyzed the H2O2-dependent oxidative coupling of 7-hydroxy-4-methylcoumarin to form four new dimers (1–4) and two known ones …

Leah Pandiscia, PhD