Title
Pterolobirins A and B, Oxygen-Bridged Cassane Diterpenoid Dimers from the Fruits of Pterolobium macropterum
Author
Achara Raksat, Thammarat Aree, Khanitha Pudhom
Year
2020
Journal
Journal of Natural Products
Abstract
Two dimeric cassane diterpenoids with an unprecedented 6/6/6/6/6/5/6/6/6 nonacyclic framework, pterolobirins A and B (1 and 2), were isolated from the fruits of Pterolobium macropterum. Their structures were assigned by interpreting the spectroscopic data. The absolute configuration of 1 was unequivocally confirmed by single-crystal X-ray diffraction data. A putative biosynthetic pathway is proposed based on a regular intermolecular Diels–Alder reaction and an intramolecular nucleophilic addition.
Instrument
J-815
Keywords
Circular dichroism, Absolute configuration, Natural products