Synthesis of plant-mediated silver nanoparticles using ficus microcarpa leaf extract and evaluation of their antibacterial activities

July 30, 2019

Title

Synthesis of plant-mediated silver nanoparticles using ficus microcarpa leaf extract and evaluation of their antibacterial activities

Author

P. Shanmuga Praba, V. S.Vasantha, J . Jeyasundari and Y. Brightson, Arul Jacob

Year

2015

Journal

European Chemical Bulletin

Abstract

In the present work, synthesis of silver nanoparticles has been done using a particular variety of medicinal plant extract. Silver nanoparticles have unique optical, electrical, and thermal properties that play an indispensable role in drug delivery, diagnostics, imaging, sensing, gene delivery, artificial implants and tissue engineering. . We used an environmentally friendly extracellular biosynthetic technique for the production of the AgNPs. The reducing agents used to produce the nanoparticles were from aqueous extracts made from the leaves of Ficus microcarpa. We have synthesized silver nano particles by adding the 80ml of 1mM silver nitrate solution into the plant extract and characterized by UV-Vis absorption spectroscopy, Infra-red spectroscopy. The UV-Visible spectrum showed a peak at 451 nm corresponding to the Plasmon absorbance of the AgNPs. Moreover, use of plant extracts also reduces the cost of microorganism isolation and culture media enhancing the cost competitive feasibility over nanoparticle synthesis by microorganisms. The antibacterial efficacy also determined by disc diffusion method with Bacillus cereus, Escherchia coli, Klebsiella pneumonia, Staphylococcus aureus and it showed that high level of inhibition. Further, efficient antimicrobial activity of the synthesized silver nanoparticles proves the application potential of green synthesis in the area of nano-medicine

Instrument

IRT-7000

Keywords

FTIR microscopy, Plant extracts, Ficus microcarpa, silver nanoparticle synthesis and antibacterial activity