Effects of interface mutations on the dimerization of alanine glyoxylate aminotransferase and implications in the mistargeting of the pathogenic variants F152I and I244T

2016 / Biochimie

In this work the dimerization process of the minor allelic form of human alanine glyoxylate aminotransferase, a pyridoxal 5′-phosphate enzyme,… Continue reading Effects of interface mutations on the dimerization of alanine glyoxylate aminotransferase and implications in the mistargeting of the pathogenic variants F152I and I244T

Leah Pandiscia, PhD

Physicochemical Properties of Micelles of Poly(styrene-b-[3-(methacryloylamino)propyl]trimethylammonium chloride-b-ethylene oxide) in Aqueous Solutions

2009 / Langmuir

Polymeric micelles from a new triblock copolymer, polystyrene-block-poly[(3-(methacryloylamino)propyl)trimethylammonium chloride]-block-poly(ethylene oxide) (PS-b-PMAPTAC-b-PEO), were prepared in aqueous solutions and characterized by various… Continue reading Physicochemical Properties of Micelles of Poly(styrene-b-[3-(methacryloylamino)propyl]trimethylammonium chloride-b-ethylene oxide) in Aqueous Solutions

Leah Pandiscia, PhD

Dissymmetric thiosemicarbazone ligands containing substituted aldehyde arm and their ruthenium(II) carbonyl complexes with PPh3/AsPh3 as ancillary ligands: Synthesis, structural characterization, DNA/BSA interaction and in vitroanticancer activity

2014 / Journal of Organometallic Chemistry

A serious of new dissymmetric ruthenium(II) carbonyl complexes of the type [Ru(CO)(EPh3)(L1–2)] (1–4), [E = P or As; L1 = N4-(2-Hydroxy-5-chlorobenzylidene)-2-amino-5-chlorobenzophenone thiosemicarbazone; L2 = N4-(2-Hydroxynaphthalene-1-carbaldehyde)-2-amino-5-chlorobenzophenone thiosemicarbazone] have been… Continue reading Dissymmetric thiosemicarbazone ligands containing substituted aldehyde arm and their ruthenium(II) carbonyl complexes with PPh3/AsPh3 as ancillary ligands: Synthesis, structural characterization, DNA/BSA interaction and in vitroanticancer activity

Leah Pandiscia, PhD

Fabrication of Colorless Organic Materials Exhibiting White Luminescence Using Normal and Excited-State Intramolecular Proton Transfer Processes

2011 / Applied Materials & Interfaces

Organic, white luminescent materials were fabricated using a mixture of proton-transfer and nonproton-transfer fluorophores. 2′-Methoxy and 2′-hydroxy derivatives of 2-phenylimidazo[1,2-a]pyridine… Continue reading Fabrication of Colorless Organic Materials Exhibiting White Luminescence Using Normal and Excited-State Intramolecular Proton Transfer Processes

Leah Pandiscia, PhD

Photocatalytic activity of novel AgBr/WO3 composite photocatalyst under visible light irradiation for methyl orange degradation

2011 / Journal of Hazardous Materials

A novel AgBr/WO3 composite photocatalyst was synthesized by loading AgBr on WO3substrate via deposition–precipitation method and characterized by XRD, SEM and… Continue reading Photocatalytic activity of novel AgBr/WO3 composite photocatalyst under visible light irradiation for methyl orange degradation

Leah Pandiscia, PhD

One pot synthesis of structurally different mono and dimeric Ni(II) thiosemicarbazone complexes and N-arylation on a coordinated ligand: a comparative biological study

2012 / Dalton Transactions

One pot synthesis of three structurally different Ni(II) thiosemicarbazone complexes 1, 2 and 3were obtained from the reaction between [NiCl2(PPh3)2], 1,2-bis(diphenylphosphino)ethane, and [H2-(Sal-tsc)]. The obtained… Continue reading One pot synthesis of structurally different mono and dimeric Ni(II) thiosemicarbazone complexes and N-arylation on a coordinated ligand: a comparative biological study

Leah Pandiscia, PhD

Design and Synthesis of a Fluorescent Probe for Zn2+, 5,7-Bis(N,N-dimethylaminosulfonyl)-8-hydroxyquinoline-Pendant 1,4,7,10-Tetraazacyclododecane and Zn2+-Dependent Hydrolytic and Zn2+-Independent Photochemical Reactivation of Its Benzenesulfonyl-Caged Derivative

2010 / Inorganic Chemistry

We previously reported on a 8-quinolinol-pendant cyclen (L5) as a Zn2+ fluorophore (cyclen = 1,4,7,10-tetraazacyclododecane) and its caged derivative, 8-(benzenesulfonyloxy)-5-(N,N-dimethylaminosulfonyl)quinolin-2-ylmethyl-pendant cyclen… Continue reading Design and Synthesis of a Fluorescent Probe for Zn2+, 5,7-Bis(N,N-dimethylaminosulfonyl)-8-hydroxyquinoline-Pendant 1,4,7,10-Tetraazacyclododecane and Zn2+-Dependent Hydrolytic and Zn2+-Independent Photochemical Reactivation of Its Benzenesulfonyl-Caged Derivative

Leah Pandiscia, PhD

Aptamer-Capped Multifunctional Mesoporous Strontium Hydroxyapatite Nanovehicle for Cancer-Cell-Responsive Drug Delivery and Imaging

2012 / Biomacromolecules

A novel cancer-cells-triggered controlled-release gadolinium-doped luminescent and mesoporous strontium hydroxyapatite nanorods (designated as Gd:SrHap nanorods) system using cell-type-specific aptamers as… Continue reading Aptamer-Capped Multifunctional Mesoporous Strontium Hydroxyapatite Nanovehicle for Cancer-Cell-Responsive Drug Delivery and Imaging

Leah Pandiscia, PhD