Antioxidant Benzoylated Flavan-3-ol Glycoside from Celastrusorbiculatus

July 28, 2017

Title

Antioxidant Benzoylated Flavan-3-ol Glycoside from Celastrusorbiculatus

Author

Bang Yeon Hwang, Hang Sub Kim, Jeong Hyeong Lee, Young Soo Hong, Jai Seup Ro, Kyong Soon Lee, Jung Joon Lee

Year

2001

Journal

Journal of Natural Products

Abstract

A new flavan-3-ol glycoside, (−)-epicatechin-5-O-β-d-glucosyl-3-benzoate (1), and two known compounds, (−)-epicatechin and (−)-epiafzelechin, were isolated from an EtOAc extract ofCelastrus orbiculatus aerial parts that exhibited significant antioxidant effect in a 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radical assay. The structure of 1 was elucidated by spectroscopic analyses, and compound 1 and its aglycon, (−)-epicatechin-3-benzoate (2), were found to be moderately active as antioxidants in the DPPH assay.

Instrument

J-720

Keywords

Circular dichroism, Absolute configuration, Natural products