Antibody drug separation using thermoresponsive anionic polymer brush modified beads with optimised electrostatic and hydrophobic interactions

2020 / Scientific Reports volume 10, Article number: 11896 (2020)

Antibody drugs play an important role in biopharmaceuticals, because of the specificity for target biomolecules and reduction of side effects. …

Heather Haffner

Consequence of macromolecular crowding on aggregation propensity and structural stability of haemoglobin under glycating conditions

2020 / International Journal of Biological Macromolecules

Cell interiors are extremely congested with biological macromolecules exerting crowding effect, influencing various physiognomies of protein life. Present work deals …

Leah Pandiscia, PhD

Chiral recognition and quantitative analysis of tyrosine enantiomers using L-cysteine capped CdTe quantum dots: Circular dichroism, fluorescence, and theoretical calculation studies

2020 / Microchemical Journal

In this work, L-cysteine-capped CdTe quantum dots (L-Cys/CdTe QDs) were used as novel chiral probes for in enantioselective recognition and …

Leah Pandiscia, PhD

Conformational analysis of ulvans from Ulva fasciata and their anticoagulant polycarboxylic derivatives

2020 / International Journal of Biological Macromolecules

This study investigates conformational aspects of ulvans (F2) and their polycarboxyl derivatives obtained through periodate–chlorite oxidation (C3) followed by DEAE-Sephacel …

Leah Pandiscia, PhD

Mechanistic insights into heme-mediated transcriptional regulation via a bacterial manganese-binding iron regulator, iron response regulator (Irr)

2020 / Journal of Biological Chemistry

The transcription factor iron response regulator (Irr) is a key regulator of iron homeostasis in the nitrogen-fixating bacterium Bradyrhizobium japonicum. …

Leah Pandiscia, PhD

Structure, Raman and luminescence characteristics of Zn1-xHfxO (0≤x≤0.1) nanocrystals prepared via N-(methyl)mercaptoacetamide assisted microwave approach

2020 / Ceramics International

A series of Zn1-xHfxO (0 ≤ x ≤ 0.1) nanocrystals was synthesized via the N-(methyl)mercaptoacetamide assisted microwave approach. The influence of the Hf dopant …

Leah Pandiscia, PhD

Isolation and structural characterization of bioactive compound from Aristolochia sprucei aqueous extract with anti-myotoxic activity

2020 / Toxicon: X

A bioactive compound isolated from the stem extract of Aristolochia sprucei through High Performance Liquid Chromatography (HPLC) was identified via Nuclear Magnetic …

Leah Pandiscia, PhD