To investigate the class-dependent properties of anti-viral IgM antibodies, we use membrane antigen capture activated cell sorting to isolate spike-protein-specific …
Continue reading “Potent neutralization by monoclonal human IgM against SARS-CoV-2 is impaired by class switch”
Carlos Morillo
May 16, 2022
Cadmium porphyrin cage compounds Cd1 and 113Cd1 have been synthesized from the free base porphyrin cage derivative H21 and Cd(OAc)2 ⋅ 2 …
Continue reading “113Cd as a Probe in NMR Studies of Allosteric Host-Guest-Ligand Complexes of Porphyrin Cage Compounds”
Carlos Morillo
May 16, 2022
The conformational landscape of a protein is constantly expanded by genetic variations that have a minimal impact on the function(s) …
Continue reading “Structural dynamics shape the fitness window of alanine:glyoxylate aminotransferase”
Carlos Morillo
May 16, 2022
Laser-induced forward transfer (LIFT) is a rapid laser-patterning technique for high-throughput combinatorial synthesis directly on glass slides. A lack of …
Continue reading “Automated Laser-Transfer Synthesis of High-Density Microarrays for Infectious Disease Screening”
Carlos Morillo
May 16, 2022
Carlos Morillo
May 16, 2022
Creating a security material that carries distinct information in reflective color, fluorescence, and chiroptical property will enhance anti-counterfeiting levels to …
Continue reading “Chiral Luminescent Liquid Crystal with Multi-State-Reversibility: Breakthrough in Advanced Anti-Counterfeiting Materials”
Carlos Morillo
May 16, 2022
Metal halide perovskite light-emitting diodes (LEDs) are promising for future display applications because of their excellent advantages, such as high …
Continue reading “Efficient Perovskite Light-Emitting Diodes with a Siloxane-Blended Organic Hole Transport Layer”
Carlos Morillo
May 16, 2022
Recent development of the chemical inhibitors specific to oncogenic KRAS (Kirsten Rat Sarcoma 2 Viral Oncogene Homolog) mutants revives much …
Continue reading “AIMP2-DX2 provides therapeutic interface to control KRAS-driven tumorigenesis”
Carlos Morillo
May 16, 2022
The chiral-induced spin selectivity effect enables the application of chiral organic materials for spintronics and spin-dependent electrochemical applications. It is …
Continue reading “Hybrid Chiral MoS2 Layers for Spin-Polarized Charge Transport and Spin-Dependent Electrocatalytic Applications”
Carlos Morillo
May 16, 2022
Carlos Morillo
May 16, 2022
Solution processing technology for the manufacturing of all-solid-state batteries (ASSBs) holds great promise of scalability and low cost over ball …
Continue reading “Solution Processing via Dynamic Sulfide Radical Anions for Sulfide Solid Electrolytes”
Carlos Morillo
May 16, 2022
The development of high-performance solution-processed organic light-emitting diodes (OLEDs) remains a challenge. An effective solution, highlighted in this work, is …
Continue reading “Thermally Activated Delayed Fluorescent Dendrimers that Underpin High-Efficiency Host-Free Solution-Processed Organic Light-Emitting Diodes”
Carlos Morillo
May 16, 2022
Carlos Morillo
May 16, 2022
Macrocyclic drugs are promising agents for treating a variety of diseases. However, these compounds usually present delivery limitations, such as …
Continue reading “Mechanically interlocked molecular architectures of valinomycin as cancer targeted prodrugs”
Carlos Morillo
May 16, 2022
Trait expression of natural populations often jointly depends on prevailing abiotic environmental conditions and predation risk. Copepods, for example, can …
Continue reading “The influence of predator community composition on photoprotective traits of copepods”
Carlos Morillo
May 16, 2022
Carlos Morillo
May 16, 2022
Carlos Morillo
May 16, 2022
Peroxiredoxins use a variety of thiols to rapidly reduce hydroperoxides and peroxynitrite. While the oxidation kinetics of peroxiredoxins have been …
Continue reading “Characterization of the glutathione-dependent reduction of the peroxiredoxin 5 homolog PfAOP from Plasmodium falciparum”
Carlos Morillo
May 16, 2022
This work investigated the extraction of bioactive compounds from citrus peels, an agri-food waste. Carbon dioxide (CO2), an eco-friendly solvent, …
Continue reading “Bioactive compounds extracted by liquid and supercritical carbon dioxide from citrus peels”
Carlos Morillo
May 16, 2022
In this work, we provide an in-depth structural analysis of SmeCOSe together with the first ligand-bound structures of this enzyme, …
Continue reading “Structural insights into choline-O-sulfatase reveal the molecular determinants for ligand binding”
Carlos Morillo
May 16, 2022