2019 / Phytochemistry
Eight previously undescribed compounds, including four alkaloids and five styryllactones together with 36 known compounds were isolated from the twig and leaf extracts of Goniothalamus …
Continue reading “Alkaloids and styryllactones from Goniothalamus cheliensis”
2018 / ACS Infectious Diseases
Computer-aided screening of antimicrobial peptides (AMPs) is a promising approach for discovering novel therapies against multidrug-resistant bacterial infections. Here, we …
2018 / Analyst
We have previously reported a novel method for measuring the spectral properties and orientation of fluorescent probes in solution, which …
2018 / Journal of Peptide Science
Among the insulin‐family peptides, two additional cysteine residues other than six conserved cysteines are sometimes found in invertebrate insulin‐like peptides …
2018 / Bioconjugate Chemistry
Synthetic antibacterial peptides are advanced weapons that scientists design and produce facing current treats due to harmful and mortal pathogens, …
2018 / Langmuir
Microbial extracellular electron transport occurs via the physical and electrical association of outer-membrane c-type cytochromes (OM c-Cyts) with extracellular solid …
2018 / Bioconjugate Chemistry
Manipulating the chiroptical at the nanoscale is of great importance in stereoselective reactions, enantioseparation, self assembly and biological phenoma. In …
2018 / PLoS ONE
The IGFN1 (Immunoglobulin-Like And Fibronectin Type III Domain Containing 1) gene has a role in skeletal muscle function and is …
2018 / Dalton Transactions
Eight novel Tl(I) β-oxodithioester complexes, [TlL]n (1–8) with ligands, L = methyl-3-hydroxy-3-(2-furyl)-2-propenedithioate (L1), methyl-3-hydroxy-3-(2-thienyl)-2-propenedithioate (L2), methyl-3-hydroxy-3-(3-pyridyl)-2-propenedithioate (L3), methyl-3-hydroxy-3-(4-pyridyl)-2-propenedithioate (L4), methyl-3-hydroxy-3-(9-anthracenyl)-2-propenedithioate …
2018 / Advanced Healthcare Materials
Flash nanoprecipitation (FNP) by fast mixing of drug‐containing organic solvent and water in a microchamber is a powerful and scalable …
2019 / International Journal of Biological Macromolecules
Thrombolytic agents are routinely used to dissolve blood clot by activating fibrinolytic system. Among different thrombolytic agents available, staphylokinase (SAK) is gaining …
2018 / Biochemistry
Cytochrome c peroxidases (bCcPs) are diheme enzymes required for the reduction of H2O2 to water in bacteria. There are two …
2018 / ACS Omega
Atrazine is an herbicide that is widely used in crop production at about 70 million pounds per year in the …
2018 / Organic & Biomolecular Chemistry
Baefrutones A–F (1–6), six new meroterpenoids with rare triketone-phloroglucinol-monoterpene/sesquiterpene frameworks, together with their biosynthetically related intermediate (±)-baeckenon B (7), were …
2018 / Advanced Healthcare Materials
Protein therapeutics are prone to lose their structure and bioactivity under various environmental stressors. This study reports a facile approach …
2018 / ChemBioChem
Aggregation of intrinsically disordered proteins into fibrils is implicated in many neurodegenerative diseases. Amyloid aggregation is a generic property of …
2018 / Journal of Thermal Analysis and Calorimetry
Colchicine (Col), a naturally occurring alkaloid, has been used as an anti-inflammatory, anti-fibrotic, and anti-tumor drug. The present study reports …
2019 / Colloids and Surfaces B: Biointerfaces
Atomic force microscopy, Thioflavin T (ThT) fluorescence assay, circular dichroism spectroscopy, differential scanning calorimetry, and molecular modeling techniques have been …
Continue reading “Dual effect of non-ionic detergent Triton X-100 on insulin amyloid formation”
2017 / Biochimica et Biophysica Acta (BBA) - Biomembranes
For the first time, the photoisomerization of a diarylethene moiety (DAET) in peptideconjugates was used to probe the effects of molecular …
2018 / PLoS ONE
Low expression and instability are significant challenges in the recombinant production of therapeutic peptides. The current study introduces a novel …
