Found 9617 Results / Page 481 of 481
2015 / Biochemistry
The four WW domains of human Nedd4–1 (neuronal precursor cell expressed developmentally downregulated gene 4–1) interact with the PPxY (PY)… Continue reading The Nedd4−1 WW Domain Recognizes the PY Motif Peptide through Coupled Folding and Binding Equilibria
2016 / ACS Chemical Biology
Cataract is the leading cause of blindness in the world. It results from aggregation of eye lens proteins into high-molecular-weight… Continue reading Copper and Zinc Ions Specifically Promote Nonamyloid Aggregation of the Highly Stable Human γ‑D Crystallin
2016 / Journal Physical Chemistry C
Noncovalent porphyrin deposition onto polylysinated surfaces proceeds by obeying the self-assembly rules experienced in aqueous solution. In particular, the porphyrin’s… Continue reading Spontaneous Deposition of Porphyrin-Based Layers on Polylysinated Substrates: Role of the Central Metal on Layer Structural and Sensing Properties
2016 / Biochemistry
Sliding clamp proteins are circular dimers or trimers that encircle DNA and serve as processivity factors during DNA replication. Their… Continue reading Molecular Dissection of the Homotrimeric Sliding Clamp of T4 Phage: Two Domains of a Subunit Display Asymmetric Characteristics
2016 / ACS Nano
Chiral nanostructures from metals and semiconductors attract wide interest as components for polarization-enabled optoelectronic devices. Similarly to other fields of… Continue reading Chiral Graphene Quantum Dots
2015 / Langmuir
We report the changes in the hydration dynamics around a globular protein, human serum albumin (HSA), in the presence of… Continue reading Effect of Short Chain Poly(ethylene glycol)s on the Hydration Structure and Dynamics around Human Serum Albumin
2016 / Journal Physical Chemistry B
The interaction between a quaternary benzophenanthridine alkaloid chelerythrine (herein after, CHL) and bovine serum albumin (herein after, BSA) was probed… Continue reading Molecular Aspects of the Interaction of Iminium and Alkanolamine Forms of the Anticancer Alkaloid Chelerythrine with Plasma Protein Bovine Serum Albumin
2016 / Journal of Medicinal Chemistry
Shelterin, a six-protein complex, plays a fundamental role in protecting both the length and the stability of telomeres. Repressor activator… Continue reading Design of High-Affinity Stapled Peptides To Target the Repressor Activator Protein 1 (RAP1)/Telomeric Repeat-Binding Factor 2 (TRF2) Protein−Protein Interaction in the Shelterin Complex
2016 / Langmuir
RecA is a naturally aggregating Escherichia coli protein that catalyzes the strand exchange reaction utilized in DNA repair. Previous studies have shown… Continue reading Hofmeister ion-induced changes in water structure correlate with changes in solvation of an aggregated protein complex
2016 / Journal of Agricultural and Food Chemistry
Pomace is an easy-accessible raw material for the isolation of fruit-derived compounds. Fruit consumption is associated with health-promoting effects, such… Continue reading Triterpenoic Acids from Apple Pomace Enhance the Activity of the Endothelial Nitric Oxide Synthase (eNOS)
2016 / Macromolecules
A new class of thermoresponsive dendronized polypeptides was prepared through highly efficient oxime ligation between oxyamino-substituted polylysines and aldehyde-cored oligoethylene… Continue reading Thermoresponsive Dendronized Polypeptides Showing Switchable Recognition to Catechols
2016 / Biomacromolecules
Glycosaminoglycans (GAGs) and glycoproteins are vital components of the extracellular matrix, directing cell proliferation, differentiation, and migration and tissue homeostasis.… Continue reading Supramolecular GAG-like Self-Assembled Glycopeptide Nanofibers Induce Chondrogenesis and Cartilage Regeneration
2016 / ACS Applied Materials and Interfaces
The design and development of fluorescent conjugated polyelectrolytes (CPEs) emitting in the red region of the visible spectrum is at… Continue reading New Red-Emitting Conjugated Polyelectrolyte: Stabilization by Interaction with Biomolecules and Potential Use as Drug Carriers and Bioimaging Probes
2016 / Biochemistry
Delineation of the effects of pathogenic mutations linked with familial prion diseases on the structure and misfolding of prion protein… Continue reading The Pathogenic Mutation T182A Converts the Prion Protein into a Molten Globule-like Conformation Whose Misfolding to Oligomers but Not to Fibrils Is Drastically Accelerated
2016 / Biochemistry
The transient receptor potential melastatin 8 (TRPM8) ion channel is the primary cold sensor in humans. TRPM8 is gated by… Continue reading Implications of Human Transient Receptor Potential Melastatin 8 (TRPM8) Channel Gating from Menthol Binding Studies of the Sensing Domain
2002 / Analytical Chemistry
Thermally induced protein unfolding/folding processes have been studied on α-lactalbumin and α-apolactalbumin. Experiments monitored by fluorescence and circular dichroism spectroscopic… Continue reading Detection and Resolution of Intermediate Species in Protein Folding Processes Using Fluorescence and Circular Dichroism Spectroscopies and Multivariate Curve Resolution
2005 / Biochimica et Biohpysica Acta
Circular dichroism (CD) is being increasingly recognised as a valuable technique for examining the structure of proteins in solution. However,… Continue reading How to study proteins by circular dichroism
