JASCO’s ChromNAV 2.0 is a powerful, easy-to-use Chromatography Data System (CDS) that streamlines instrument control, data acquisition, and analysis across HPLC, UHPLC, SFC, GPC, and preparative LC workflows. Its highly configurable graphical user interface (GUI) can be tailored to display only the functions needed for your application, allowing users to quickly become proficient while maximizing productivity. ChromNAV provides precise control of essential chromatographic parameters, including solvent gradients, flow rates, injection volumes, detector wavelengths, column and oven temperatures, autosampler sequences, and reporting to ensure reliable, reproducible results. Secure, audit-ready data management and comprehensive data processing tools support efficient laboratory workflows and regulatory compliance, making ChromNAV the ideal software platform for modern chromatography laboratories.
Applications
ChromNAV 2.0 is a universal CDS which can be used with any type of analytical separation, including: HPLC, UHPLC, GPC, SFC and preparative HPLC & SFC. Check out the complete suite of option applications below.
- ChromNAV Lite – for acquisition only from a single detector
- ChromNAV CFR – fully 12 CFR part II compliant version of ChromNAV, with electronic signature and complete audit trail
- ChromNAV CMS – integrated control of a single quadrapole MS detector for both LC and SFC
- ChromNAV-GPC – an add in for controlling a GPC system and calculating molecular weights
- ChromNAV-Heparins – a dedicated app for estimation of molecular weight of low molecular mass heparins
- ChromNAV Method Scouting – automated method development app for unattended column and solvent screening for both HPLC and SFC
- ChromNAV-Fraction Controller – for controlling fraction collection either by open bed fraction collector or fixed fraction valve, using timed events and threshold triggering
- ChromNAV-Stacked Injections – an app for preparative HPLC and SFC for stacked injections
Powerful System Control for Method Development
ChromNAV 2.0 offers flexible system control and data acquisition with options for 2D (or up to 4D) gradient control and multi-zone oven control (up to 3) for method development. Solvent and column selection has been increased to include up to 10 positions for both. During acquisition, the run-time for a chromatogram can be increased to capture later eluting peaks that may exceed the set run-time.
Compatible Instruments and Detectors
ChromNAV 2.0 is designed for JASCO LC instruments. It supports the full range of detectors and modules available in the LC-4000 series.
LC systems
- LC-4000 Series (HPLC, RHPLC, UHPLC, analytical SFC, and preparative HPLC/SFC configurations)
Supported Detectors
- UV-Vis (single and multi-wavelength): UV-4570, UV-4070, UV-4077
- Photodiode array (PDA): MD-4010, MD-4015, MD-4017
- Fluorescence (FP): FP-4020, FP-4025
- Refractive index (RI): RI-4030, RI-4035
- Circular dichroism (CD): CD-4095, OR-4090
- Mass spectrometry detector: expression CMS Single Quadrapole Mass Spectrometer Detector
Data Rich
During acquisition a ‘known’ chromatogram can be overlaid for visual comparison with the currently separation, as a quick indicator to the user of the reliability current separation.The fluorescence and UV-visible detectors both include the spectral scanning, which can be triggered manually, by time or by threshold. Data acquisition and analysis for PDA detectors are included as standard in ChromNAV. A newly added feature creates the ability to send an automated email to your PC or smartphone with an update on the progress of the sequence.
Green
As part of JASCO’s commitment to Green Energy, the LC-4000 Series includes both ‘power off’ for the flow, lamp, column oven etc at the end of the sequence, and a ‘soft-off’ function to automatically completely shut down selected modules to save energy.
