Hybrid SFC System Configurations

SFC-4000 Series

Hybrid SFC System

The SFC Hybrid system crosses the divide between analytical SFC and preparative SFC, offering the best of both techniques. With flow rates from 1 mL/min up to 20 mL/min this system can be used with 4.6mm columns for high-quality analytical separations and with 10 mm columns for excellent sample isolation and purification.

Semi-Preparative SFC System

Analytical to Semi-Preparative Flow Rates

Using columns from 4.6 to 10 mm ID, the Hybrid SFC System can be used for the separation and purification of up to several 100 mg of sample material.

Typical Purification Range

Analytical and semi-preparative flow rates from 1mL/min to 20mL/min for purification of samples up to 100s of mg.

Column Switching

Six or ten column switching for automatic selection for method development.

Solvent Switching

Six or ten modifier solvent selection for method development.

High-Capacity Column Oven

High-capacity column oven for up to ten 10mm columns, with an option for use of up to 3 column ovens for even greater flexibility.

High Recovery Rate

Patented individual MCS MicroCyclone fraction collection system for sample collection without cross-contamination.

Powerful Software

ChromNav for simple control with powerful fractionation algorithms.

Wide Range of Detectors

Wide range of detectors including UV-visible, Photo Diode Array (PDA), Mass Spectrometer (MS),  Flame Ionization Detector (FID), and Circular Dichroism (CD) for chiral applications.  For applications that require the utmost sensitivity, JASCO has designed the first high-pressure flow cell for the FP-4020 fluorescence detector making it compatible with SFC.

High-Throughput Fraction Collection System

Fraction collection with open bed fraction collector.

Dynamic Back Pressure Regulator

Patented dynamic back pressure regulator for accurate control of pressure for accurate and reproducible separations.