FVS-6000 Vibrational Circular Dichroism Spectrometer

A unique design with high-sensitivity and broad wavelength range 4000-750 cm-1 .

FVS-6000 Vibrational Circular Dichroism Spectrometer

Vibrational Circular Dichroism
FVS-6000 Vibrational Circular Dichroism Spectrometer

The FVS-6000 vibrational circular dichroism spectrometer measures both IR absorption and VCD, and provides accurate and highly sensitive measurement of the fingerprint region.  It also has several unique features such as a wide measurement range option of 4000-750 cm-1.

Since the CD signals in the infrared region are typically one or more orders of magnitude lower than ECD signals in the UV-Visible region, high sensitivity and stability are especially important for a VCD spectrometer.

Spectra Manager™ Suite provides the user with a simple intrument instrument interface with tools to ensure smooth VCD data acquisition and analysis. Theoretically calculated VCD intensities from ab initio calculation software can be plotted as simulated spectra to be compared with the experimental data for further tertiary structure analysis of molecules.

Optimized Optics

The FVS-6000 optical system uses a 28 deg interferometer for high throughput and to minimize polarization effects with reflective optics to eliminate artifacts caused by birefringence, resulting in very high-quality VCD data.

 

Thermal Stability

Thermal stability is maintained for long-term baseline stability by isolating the IR light source (high intensity ceramic light source), with thermal control of the photoelastic modulator and detector, which are all required for long duration measurements.

Wide Spectral Range

The FVS-6000 uses a high sensitivity MCT detector optimized for VCD measurement across a wide spectral range from 3,200-850 cm-1. Optional detectors and filters can be added to extend the range to 4000-750 cm-1, for measurement of OH and NH bands. Detectors can be easily exchanged without the need for manual alignment,  and optical filters on a 6-position wheel can be switched automatically.

Narrow Band Mode

The ‘narrow band mode’ allows measurements of small peaks at targeted absorption bands with high sensitivity using optional band pass filters.

VCD Auto-Alignment

The auto-alignment function optimizes the VCD optics to reduce linear anisotropy artifacts. No manual alignment is required when the detector and/or optical filters are exchanged.

Lock-in Detection with DSP

Phase-sensitive lock-in detection uses DSP (Digital Signal Processing) with a sophisticated algorithm optimized for VCD and offers dramatic improvement in the S/N ratio, particularly compared to more complicated optical designs.

Purge

The interferometer and optics, sample chamber and detector housing are  purgeable for high-precision data free from the interferences from environmental gases.

  • Optional accessory for auto-sampling
  • Detector with extra large LN2 dewar for up to 15 hours of operation without refill