Vibrational Circular Dichroism Spectrometer


FVS-6000 Vibrational Circular Dichroism Spectrometer

Vibrational Circular Dichroism
FVS-6000 Vibrational Circular Dichroism Spectrometer

The FVS-6000 vibrational circular dichroism spectrometer measures both IR absorption and VCD and provides accurate and highly sensitive measurements in the fingerprint region. It also has several unique features such as a wide measurement range option of 4,000 to 750 cm-1 with a choice of detectors

Since the VCD signals in the infrared region are typically one or more orders of magnitude lower than ECD signals in the UV-Visible region, high sensitivity and stability are especially important for a VCD spectrometer.

Spectra Manager™ Suite provides a simple user interface with tools that ensure excellent VCD data acquisition and analysis. Theoretically, calculated VCD spectra from ab initio calculation software (such as Schrodinger Jaguar or Gaussian) can be plotted as the theoretical spectra compared with the experimental data for further tertiary structure analysis of molecules.

Optimized Optics

The FVS-6000 optical system uses a 28° interferometer with gold-coated corner cube mirrors for high throughput and to minimize polarization effects with reflective optics to eliminate artifacts caused by birefringence, resulting in very high-quality VCD data.

Thermal Stability

Multi-zone temperature control with feedback monitoring throughout the optical bench ensures that thermal stability is well maintained for the long-term baseline stability required for long duration measurements. The key components of the high-intensity ceramic light source, photo-elastic modulator, interferometer, sample compartment, and detector are separately controlled.

Wide Spectral Range

The FVS-6000 uses a unique highly sensitive narrow-band MCT detector specially developed for VCD measurement across the spectral range 3,200-850 cm-1. Optional detectors and filters can be added to extend the range to 4,000-750 cm-1,  typically for measurement of OH and NH bands. Detectors are easily exchanged without the need for manual alignment,  and optical filters can be selected automatically.

Narrow Band Mode

The ‘narrow band mode’ allows measurements of small peaks at targeted absorption bands with high sensitivity using optional band-pass filters.

VCD Auto-Alignment

The auto-alignment function optimizes the VCD optics to reduce linear anisotropy artifacts. No manual alignment is required when the detector and/or optical filters are exchanged.

Lock-in Detection with DSP

Phase-sensitive lock-in detection uses DSP (Digital Signal Processing) with a sophisticated algorithm optimized for VCD and offers a dramatic improvement in the S/N ratio, particularly compared to more complicated optical designs.


The interferometer and optics, sample chamber, and detector housing are all independently purgeable with N2 for high-precision data free of interference from atmospheric gases.

Long Term stable Measurement

The FVS-6000 MCT detector includes an extra large LN2 dewar for up to 15 hours of operation without refill

Optional accessories

  • Auto-sampling – Automatic sampling is useful for unattended operation for long duration spectral accumulations. The TAS-FVS autosampler can be used for both background and sample measurements.
  • Sample rotation – For samples that have linear dichroism or birefringence, rotation can be a useful method for identifying and minimizing the effects. The SRU-FVS can be set up for unattended operation to analyze the sample in different orientations and collect spectra for comparison.