The abundance of plasma membrane-resident receptors and transporters has to be tightly regulated by ubiquitin-mediated endosomal degradation for the proper …
Continue reading “Lipid-mediated activation of plasma membrane-localized deubiquitylating enzymes modulate endosomal trafficking”
Carlos Morillo
November 14, 2022
Coronavirus infections are a world-wide threat to human health. A promising strategy to develop a broadly active antiviral is the …
Continue reading “Multimeric ACE2-IgM fusions as broadly active antivirals that potently neutralize SARS-CoV-2 variants”
Carlos Morillo
November 14, 2022
Nicotinamide adenine dinucleotide (NAD) is an essential cofactor for numerous enzymes involved in energy metabolism. Because decreasing NAD levels is …
Continue reading “Porcine placental extract increase the cellular NAD levels in human epidermal keratinocytes”
Carlos Morillo
November 14, 2022
Unintentionally doped (001)-oriented orthorhombic κ-Ga2O3 epitaxial films on c-plane sapphire substrates are characterized by the presence of ≈ 10 nm …
Continue reading “Silane-Mediated Expansion of Domains in Si-Doped κ-Ga2O3 Epitaxy and its Impact on the In-Plane Electronic Conduction”
Carlos Morillo
November 14, 2022
Mutual interference between surface ligands on multifunctional nanoparticles remains a significant obstacle to achieving optimal drug-delivery efficacy. Here, we develop …
Continue reading “Ligand-switchable nanoparticles resembling viral surface for sequential drug delivery and improved oral insulin therapy”
Carlos Morillo
November 14, 2022
Fabricating microscale helical structures from small molecules remains challenging due to the disfavoured torsion energy of twisted architectures and elusory …
Continue reading “Hierarchically self-assembled homochiral helical microtoroids”
Carlos Morillo
November 14, 2022
The use of separators that are thinner than conventional separators (> 20 µm) would improve the energy densities and specific energies …
Continue reading “An improved 9 micron thick separator for a 350 Wh/kg lithium metal rechargeable pouch cell”
Carlos Morillo
November 14, 2022
DNA:DNA:RNA triplexes that are formed through Hoogsteen base-pairing of the RNA in the major groove of the DNA duplex have …
Continue reading “HIF1α-AS1 is a DNA:DNA:RNA triplex-forming lncRNA interacting with the HUSH complex”
Carlos Morillo
November 14, 2022
The synthesis and characterization of diketopyrrolopyrroles and perylenemonoimidodiesters linked to a substituted benzoic acid in the ortho, meta, and para …
Continue reading “Disentangling Excimer Emission from Chiral Induction in Nanoscale Helical Silica Scaffolds Bearing Achiral Chromophores”
Carlos Morillo
November 14, 2022
Radiography is non-destructive imaging for engineering, medical diagnostics, airport security checks, and decontamination activities in nuclear plants. Inorganic scintillators are …
Continue reading “High-throughput production of LuAG-based highly luminescent thick film scintillators for radiation detection and imaging”
Carlos Morillo
November 14, 2022
Future spintronics and quantum technologies will require a portfolio of techniques for manipulating electron spins in functional nanodevices. Especially, the …
Continue reading “Polarization-controlled tunable directional spin-driven photocurrents in a magnetic metamaterial with threefold rotational symmetry”
Carlos Morillo
November 14, 2022
The polystyrene (PS) retrieved from the beach exhibited no change in surface texture. In contrast to it, the retrieved polypropylene …
Continue reading “Degradation and fragmentation behavior of polypropylene and polystyrene in water”
Carlos Morillo
November 14, 2022
A grand challenge in terpene synthase (TS) enzymology is the ability to predict function from protein sequence. Given the limited …
Continue reading “Structure-guided product determination of the bacterial type II diterpene synthase Tpn2”
Carlos Morillo
November 14, 2022
Stability of eukaryotic mRNAs is associated with their codon, amino acid, and GC content. Yet, coding sequence motifs that predictably …
Continue reading “A nascent peptide code for translational control of mRNA stability in human cells”
Carlos Morillo
November 14, 2022
This study focuses on obtaining and characterizing novel chitosan-based biomaterials containing cannabis oil to potentially promote wound healing. The primary …
Continue reading “Chitosan-based films with cannabis oil as a base material for wound dressing application”
Carlos Morillo
November 14, 2022
The human light modulation response allows humans to perceive objects clearly by receiving the appropriate amount of light from the …
Continue reading “A biomimetic ocular prosthesis system: emulating autonomic pupil and corneal reflections”
Carlos Morillo
November 14, 2022
Slip length describes the classical no-slip boundary condition violation of Newtonian fluid mechanics, where fluids glide on the solid surfaces. …
Continue reading “Unraveling the liquid gliding on vibrating solid liquid interfaces with dynamic nanoslip enactment”
Carlos Morillo
November 14, 2022
The emerging SARS-CoV-2 variants, commonly with many mutations in S1 subunit of spike (S) protein are weakening the efficacy of …
Continue reading “A variant-proof SARS-CoV-2 vaccine targeting HR1 domain in S2 subunit of spike protein”
Carlos Morillo
November 14, 2022
Functional peptides, which are composed of proteinogenic natural amino acids, are expected to be used as biomaterials with minimal environmental …
Continue reading “Development of truncated elastin-like peptide analogues with improved temperature-response and self-assembling properties”
Carlos Morillo
November 14, 2022
Carlos Morillo
November 1, 2022