A Vibrational and Electronic Circular Dichroism Study of Chiral Seleno Compounds Prepared from a Novel Naphthol based Diselenide.
Francesca Mangiavacchi, Giuseppe Mazzeo, Maria Chiara Graziani, Francesca Marini, Józef Drabowicz, Ewelina Wielgus, Luca Sancineto, Giovanna Longhi, Riccardo Vivani, Sergio Abbate, Claudio Santi
The base induced activation of β-naphthol toward the electrophilic aromatic substitution has been used for the synthesis of the unprecedent 1,1'-diselanediylbis(naphthalen-2-ol) fully characterized by means of NMR and X-Ray analysis. Its reactivity was studied and the synthesis of novel chiral selenium containing heterocycles was discovered. Chiroptical methods (VCD and ECD) were successfully used to define their absolute configuration and these results represent the first example reported for organoselenium derivatives.
Circular Dichroism, Chiral, VCD