Title
Asymmetric Synthesis and Stereochemical Assignment of 12C/13C Isotopomers
Author
Tomoya Miura, Takayuki Nakamuro, Yuuya Nagata, Daisuke Moriyama, Scott G. Stewart, and Masahiro Murakami
Year
2019
Journal
Journal of the American Chemical Society
Abstract
A synthesis of chiral hydrocarbons having C1 axis and C3 symmetry, which owe their chirality due to asymmetrical distribution of 12C/13C isotopes, is reported. Their absolute configurations assigned using the vibrational circular dichroism technique conform with those deduced from the absolute configurations of the parent α-formyl cyclopropanes.
Instrument
VCD, FVS-6000
Keywords
FVS-6000, chiral, vibrational circular dichroism, isotopomers, α-formyl cyclopropanes