Title
Chemical Constituents Isolated from Bletilla striataand Their Inhibitory Effects on Nitric Oxide Production in RAW 264.7 Cells
Author
Bae Joon Young, Lee Jin Woo, Jin Qinghao, Jang Hari, Lee Dongho, Kim Youngsoo, Hong Jin Tae, Lee Mi Kyeong, Lee Moon Soon, Hwang Bang Yeon
Year
2016
Journal
Chemistry & Biodiversity
Abstract
Bioassay-guided fractionation of the MeOH extract of the tubers of Bletilla striata led to the isolation of two new C-methylated flavan-3-ols, bletillanols A (1) and B (2), along with ten known compounds (3-12). Their structures were determined by using extensive spectroscopic analysis including 1D-, 2D-NMR and circular dichroism data. All of the isolated compounds were tested for their inhibitory potential on the nitric oxide generation in LPS-stimulated RAW 264.7 cells.
Instrument
J-715
Keywords
Circular dichroism, Absolute configuration, Agricultural and environmental, Pharmaceutical,