Computed optical spectra of SARS-CoV-2 proteins

March 7, 2023

Title

Computed optical spectra of SARS-CoV-2 proteins

Author

Zhuo Li, Jonathan D. Hirst

Year

2020

Journal

Chemical Physics Letters 758 (2020) 137935

Abstract

Treatment for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus that causes Covid-19, may well be predicated on knowledge of the structures
of protein of this virus. However, often these cannot be determined easily or quickly. Herein, we provide calculated circular dichroism (CD) spectra in the far- and
near-UV, and infra-red (IR) spectra in the amide I region for experimental structures and computational models of SARS-CoV-2 proteins. The near-UV CD spectra offer
greatest sensitivity in assessing the accuracy of models.