Computed optical spectra of SARS-CoV-2 proteins
Zhuo Li, Jonathan D. Hirst
Chemical Physics Letters 758 (2020) 137935
Treatment for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus that causes Covid-19, may well be predicated on knowledge of the structures
of protein of this virus. However, often these cannot be determined easily or quickly. Herein, we provide calculated circular dichroism (CD) spectra in the far- and
near-UV, and infra-red (IR) spectra in the amide I region for experimental structures and computational models of SARS-CoV-2 proteins. The near-UV CD spectra offer
greatest sensitivity in assessing the accuracy of models.