Fabrication of capsaicin functionalized reduced graphene oxide and its effect on proliferation and differentiation of osteoblasts

August 9, 2018

Title

Fabrication of capsaicin functionalized reduced graphene oxide and its effect on proliferation and differentiation of osteoblasts

Author

Liansuo Zhai, Lin Li,Qi Zhang

Year

2018

Journal

Environmental Toxicology and Pharmacology

Abstract

Herein, we report a new simple and biological approach for the preparation of capsaicin adsorbed reduced graphene oxide (RGO), where capsaicin acts as a stabilizing and deoxygenating agent. The capsaicin that is decorated on graphene surface plays an important role as a capping agent to avoid the aggregation of graphene sheets. The capsaicin functionalized RGO stimulated the differentiation and proliferation of osteoblasts to a larger extent, which is a significant feature for the use of biomaterials in biomedical application such as in bone tissue engineering, more speciafically in the case of diseases such as osteoporosis.

Instrument

FTIR 4100

Keywords

FTIR Microscopy, Capsaicin, Osteoblasts, Graphene, Differentiation, Manufacturing