Cataract is the leading cause of blindness in the world. It results from aggregation of eye lens proteins into high-molecular-weight… Continue reading Copper and Zinc Ions Specifically Promote Nonamyloid Aggregation of the Highly Stable Human γ‑D Crystallin
Leah Pandiscia, PhD
July 24, 2017
Noncovalent porphyrin deposition onto polylysinated surfaces proceeds by obeying the self-assembly rules experienced in aqueous solution. In particular, the porphyrin’s… Continue reading Spontaneous Deposition of Porphyrin-Based Layers on Polylysinated Substrates: Role of the Central Metal on Layer Structural and Sensing Properties
Leah Pandiscia, PhD
July 24, 2017
Leah Pandiscia, PhD
July 24, 2017
Chiral nanostructures from metals and semiconductors attract wide interest as components for polarization-enabled optoelectronic devices. Similarly to other fields of… Continue reading Chiral Graphene Quantum Dots
Leah Pandiscia, PhD
July 24, 2017
Leah Pandiscia, PhD
July 24, 2017
Leah Pandiscia, PhD
July 24, 2017
Leah Pandiscia, PhD
July 24, 2017
RecA is a naturally aggregating Escherichia coli protein that catalyzes the strand exchange reaction utilized in DNA repair. Previous studies have shown… Continue reading Hofmeister ion-induced changes in water structure correlate with changes in solvation of an aggregated protein complex
Leah Pandiscia, PhD
July 24, 2017
Pomace is an easy-accessible raw material for the isolation of fruit-derived compounds. Fruit consumption is associated with health-promoting effects, such… Continue reading Triterpenoic Acids from Apple Pomace Enhance the Activity of the Endothelial Nitric Oxide Synthase (eNOS)
Leah Pandiscia, PhD
July 24, 2017
A new class of thermoresponsive dendronized polypeptides was prepared through highly efficient oxime ligation between oxyamino-substituted polylysines and aldehyde-cored oligoethylene… Continue reading Thermoresponsive Dendronized Polypeptides Showing Switchable Recognition to Catechols
Leah Pandiscia, PhD
July 24, 2017
Glycosaminoglycans (GAGs) and glycoproteins are vital components of the extracellular matrix, directing cell proliferation, differentiation, and migration and tissue homeostasis.… Continue reading Supramolecular GAG-like Self-Assembled Glycopeptide Nanofibers Induce Chondrogenesis and Cartilage Regeneration
Leah Pandiscia, PhD
July 24, 2017
Leah Pandiscia, PhD
July 24, 2017
Leah Pandiscia, PhD
July 24, 2017
Leah Pandiscia, PhD
July 24, 2017
Thermally induced protein unfolding/folding processes have been studied on α-lactalbumin and α-apolactalbumin. Experiments monitored by fluorescence and circular dichroism spectroscopic… Continue reading Detection and Resolution of Intermediate Species in Protein Folding Processes Using Fluorescence and Circular Dichroism Spectroscopies and Multivariate Curve Resolution
Leah Pandiscia, PhD
July 13, 2017
Circular dichroism (CD) is being increasingly recognised as a valuable technique for examining the structure of proteins in solution. However,… Continue reading How to study proteins by circular dichroism
Leah Pandiscia, PhD
July 13, 2017