Title
Utilization of the Pleiotropy of a Peptidic Aptamer To Fabricate Heterogeneous Nanodot-Containing Multilayer Nanostructures
Author
Ken-Ichi Sano, Hiroyuki Sasaki, Kiyotaka Shiba
Year
2006
Journal
JACS
Abstract
Peptide aptamers (=binders) against inorganic materials often show a capacity for mineralization of their target atoms; thus they are able to function both as binding molecules and as mediators for mineralization. Although the mechanisms underlying these two properties of peptide aptamers are not yet fully understood, they have been used separately to fabricate various nanostructures. Here, we present a novel method of nanofabrication, in which binding and mineralization by a peptide aptamer are alternately utilized to assemble multilayered nanostructures comprised of metal loaded cage proteins ornamented with Ti-binding peptides.
Full Article
Instrument
FP-6500
Keywords
Fluorescence, Nanostructures, Ligand binding, Biochemistry, Materials