Leah Pandiscia, PhD
March 24, 2020
Amyloid formation is a process involving interconverting protein species and results in toxic oligomers and fibrils. Aggregated alpha-synuclein (αS) participates… Continue reading Alpha-synuclein stepwise aggregation reveals features of an early onset mutation in Parkinson’s disease
Leah Pandiscia, PhD
March 24, 2020
Leah Pandiscia, PhD
March 24, 2020
Protein–protein interactions that can be controlled by environmental triggers have immense potential in various biological and industrial applications. In the… Continue reading Histidine-Mediated Intramolecular Electrostatic Repulsion for Controlling pH-Dependent Protein–Protein Interaction
Leah Pandiscia, PhD
March 24, 2020
Leah Pandiscia, PhD
March 24, 2020
Transient absorption spectroscopy in combination with in silico methods has been employed to study the interactions between human serum albumin (HSA) and… Continue reading Investigation of metabolite-protein interactions by transient absorption spectroscopy and in silico methods
Leah Pandiscia, PhD
March 24, 2020
The photochemical hydrogen evolution capabilities of paddlewheel‐type dirhodium complexes with electron withdrawing carboxylates, [Rh2(O2CR)4(H2O)2] (R=CF3 and CCl3 for [2(H2O)2] and [3(H2O)2], respectively),… Continue reading Experimental and Theoretical Study of Photochemical Hydrogen Evolution Catalyzed by Paddlewheel‐Type Dirhodium Complexes with Electron Withdrawing Carboxylate Ligands
Leah Pandiscia, PhD
March 24, 2020
The protective mechanism of glycerol on β-lactoglobulin were studied in 0–60% glycerol solutions by experimental and molecular simulation approaches. Results… Continue reading Glycerol induced stability enhancement and conformational changes of β-lactoglobulin
Leah Pandiscia, PhD
March 24, 2020
Leah Pandiscia, PhD
March 24, 2020
Yb(III), Sm(III) and La(III) complexes of a tetradentate Schiff base ligand, bis(pyridoxylidene)ethyelenediamine, are reported. Single crystal X-ray structures of the… Continue reading Yb(III), Sm(III) and La(III) complexes of a tetradentate pyridoxal Schiff base ligand: Their DNA-binding activity and bio-imaging applications
Leah Pandiscia, PhD
March 24, 2020
The Staphylococcus aureus Extracellular Adherence Protein (Eap) and its homologs, EapH1 and EapH2, are a family of secreted proteins that potently inhibit the neutrophil… Continue reading Staphylococcus aureus evasion proteins EapH1 and EapH2: Residue-level investigation of an alternative binding motif for human neutrophil elastase
Leah Pandiscia, PhD
March 24, 2020
In this manuscript we present a spectroscopic study of the supramolecular interaction of photo-switchable 4,4′-Azobenzene dicarboxylic acid (ADA) with L… Continue reading Spectroscopic study of the pH dependent interaction of an achiral molecular photo-switch with poly-Glutamic acid
Leah Pandiscia, PhD
March 24, 2020
Leah Pandiscia, PhD
March 24, 2020
The effects of low frequency magnetic field on myoglobin (Mb) oxidation stability were evaluated by treatments at 0, 3, 6,… Continue reading Effects of low frequency magnetic field on myoglobin oxidation stability
Leah Pandiscia, PhD
March 24, 2020
A peptide (FFACD) can form hydrogels in DMSO-H2O mixtures (G1), NaOH (G2) and L-arginine (G3) aqueous solutions, respectively. Methyl thiazolyl… Continue reading Peptide-assembled hydrogels for pH-controllable drug release
Leah Pandiscia, PhD
March 24, 2020
Leah Pandiscia, PhD
March 24, 2020
Leah Pandiscia, PhD
March 24, 2020
Apohemoglobin (apoHb) is a dimeric globular protein with two vacant heme‐binding pockets that can bind heme or other hydrophobic ligands.… Continue reading Novel manufacturing method for producing apohemoglobin and its biophysical properties
Leah Pandiscia, PhD
March 24, 2020
Leah Pandiscia, PhD
March 24, 2020
Sulfur is an essential nutrient that can be converted into utilizable metabolic forms to produce sulfur-containing metabolites in plant. Adenosine… Continue reading C-Terminal Redox Domain of Arabidopsis APR1 Is a Non-Canonical Thioredoxin Domain with Glutaredoxin Function
Leah Pandiscia, PhD
March 24, 2020