Two-dimensional sheet-like supramolecules have attracted much attention from the viewpoints of their potential application as functional (nano)materials due to unique… Continue reading Bioinspired supramolecular nanosheets of zinc chlorophyll assemblies
Leah Pandiscia, PhD
March 24, 2020
HIV-1 Gag is a highly flexible multidomain protein that forms the protein lattice of the immature HIV-1 virion. In vitro, it… Continue reading Nucleic acid-induced dimerization of HIV-1 Gag protein
Leah Pandiscia, PhD
March 24, 2020
An alternative photo-cross-linker having a D-threoninol skeleton instead of the 2′-deoxyribose backbone in 3-cyanovinylcarbazole (CNVK) was investigated to improve the photoreactivity… Continue reading DNA photo-cross-linking using a pyranocarbazole-modified oligodeoxynucleotide with a D-threoninol linker
Leah Pandiscia, PhD
March 24, 2020
DEAD-box helicase 3, X-linked (DDX3X) regulates the retinoic acid-inducible gene I (RIG-I)-like receptor (RLR)-mediated antiviral response, but can also be… Continue reading Exportin-1-Dependent Nuclear Export of DEAD-box Helicase DDX3X is Central to its Role in Antiviral Immunity
Leah Pandiscia, PhD
March 24, 2020
Dietary phenolic compounds display strong antioxidant capabilities but face limited practical applications as a result of their poor biocompatibility (high… Continue reading Improving Antioxidant Activity of β-Lactoglobulin by Nature-Inspired Conjugation with Gentisic Acid
Leah Pandiscia, PhD
June 29, 2020
In our continuing search for novel natural products with antiplasmodial activity, an extract of Aniba citrifolia was found to have good activity,… Continue reading Anibamine and Its Analogues: Potent Antiplasmodial Agents from Aniba citrifolia
Leah Pandiscia, PhD
March 24, 2020
Leah Pandiscia, PhD
March 24, 2020
Id helix-loop-helix (HLH) proteins (Id1–4) bind E protein bHLH transcription factors, preventing them from forming active transcription complexes that drive… Continue reading A Small-Molecule Pan-Id Antagonist Inhibits Pathologic Ocular Neovascularization
Leah Pandiscia, PhD
March 24, 2020
Self-assembled supramolecular organic materials with π-functionalities are of great interest because of their applications as biocompatible nanoelectronics. A detailed understanding… Continue reading Controlling Supramolecular Chirality in Peptide−π-Peptide Networks by Variation of the Alkyl Spacer Length
Leah Pandiscia, PhD
March 24, 2020
In this study, a novel zero-dimensional (0D)/two-dimensional (2D) heterojunction photocatalyst consisting of cadmium sulfide (CdS) nanosheets (NSs) decorated with FeP… Continue reading Highly efficient photocatalytic hydrogen evolution from 0D/2D heterojunction of FeP nanoparticles/CdS nanosheets
Leah Pandiscia, PhD
March 24, 2020
The present research relates to a fusion protein comprising a chromogenic blue ultramarine protein (UM) bound to a keratin-based peptide… Continue reading Fusion proteins with chromogenic and keratin binding modules
Leah Pandiscia, PhD
March 24, 2020
Leah Pandiscia, PhD
March 24, 2020
Leah Pandiscia, PhD
March 24, 2020
The heat-induced aggregation of edible proteins has been regarded as one of the critical challenges for their application in protein-enriched… Continue reading Enhancing the thermal stability of soy proteins by preheat treatment at lower protein concentration
Leah Pandiscia, PhD
March 24, 2020
Biochemical and gelling properties of silver carp surimi as affected by harvesting season and chopping process were investigated. Myosin from… Continue reading Biochemical and gelling properties of silver carp surimi as affected by harvesting season and chopping time
Leah Pandiscia, PhD
March 24, 2020
Solanum indicum var. recurvatum, distributed mainly in Hekou, Simao and Menghai areas of Yunnan province, China, is characterized by stellate pubescent leaves… Continue reading Two new 23S,26R-hydroxylated spirostanoid saponins from the fruits of Solanum indicum var. recurvatum
Leah Pandiscia, PhD
March 24, 2020
The successful management of tuberculosis (TB) requires efficient diagnosis and treatment. Further, the increasing prevalence of drug-resistant TB highlights the… Continue reading Theranostic Application of a Novel G-Quadruplex-Forming DNA Aptamer Targeting Malate Synthase of Mycobacterium tuberculosis
Leah Pandiscia, PhD
March 24, 2020
Microbes serve as the most important resource for drug discovery. During our screening for bioactive compounds from our natural products… Continue reading Brocaeloid D, a novel compound isolated from a wheat pathogenic fungus, Microdochium majus 99049
Leah Pandiscia, PhD
March 24, 2020
Alzheimer’s disease (AD) is a neurodegenerative disorder caused by protein misfolding, aggregation and accumulation in the brain. A large number… Continue reading Baicalein suppresses Repeat Tau fibrillization by sequestering oligomers
Leah Pandiscia, PhD
March 24, 2020
Leah Pandiscia, PhD
March 24, 2020