Novel hydrogel@liposome particles were prepared by pH-triggered molecular gel formation inside of liposomes loaded with a low-molecular weight gelator derived from l-valine (1).… Continue reading Liposome-Enveloped Molecular Nanogels
Leah Pandiscia, PhD
March 24, 2020
Leah Pandiscia, PhD
March 24, 2020
The proteolytic resistant 33-mer gliadin peptide is an immunodominant fragment in gluten and responsible for the celiac disease and other… Continue reading Molecular mechanisms of 33-mer gliadin peptide oligomerisation
Leah Pandiscia, PhD
March 24, 2020
Leah Pandiscia, PhD
March 24, 2020
The highest occupied molecular orbital (HOMO) level of hole-transporting polymeric materials was tuned by postfunctionalization based on a highly-efficient [2 + 2]… Continue reading Energy level tuning of aromatic polyamines by [2 + 2] cycloaddition-retroelectrocyclization for the optimization of device performances
Leah Pandiscia, PhD
March 24, 2020
Glaucoma is a leading cause of irreversible blindness worldwide. Current treatments of glaucoma involve lowering the IOP by means of… Continue reading An injectable peptide hydrogel for reconstruction of the human trabecular meshwork
Leah Pandiscia, PhD
March 24, 2020
Perfluorodecanoic acid (PFDA) has been widely used in production of many daily necessities because of its special nature. Althoughtoxic effects… Continue reading Perfluorodecanoic acid-induced oxidative stress and DNA damage investigated at the cellular and molecular levels
Leah Pandiscia, PhD
June 29, 2020
Quinoline based fluorescent probes were formulated for the precise detection of cerium ions. Probes 1 and 2 detect Ce3+ ion as opposed to other metal… Continue reading Quinoline based probes: Large blue shifted fluorescent and electrochemical sensing of cerium ion and its biological applications
Leah Pandiscia, PhD
June 29, 2020
Naturally occurring enzymatic pathways enable highly specific, rapid thiophenic sulfur cleavage occurring at ambient temperature and pressure, which may be… Continue reading Inhibition Mechanisms of Rhodococcus Erythropolis 2′-Hydroxybiphenyl-2-sulfinate Desulfinase (DszB)
Leah Pandiscia, PhD
March 24, 2020
Core double-shell MnFe2O4@reduced graphene oxide (rGO)@TiO2 magnetic photocatalyst was synthesized at different calcination temperatures using different initial amounts of graphene oxide.… Continue reading Core double-shell MnFe2O4@rGO@TiO2 superparamagnetic photocatalyst for wastewater treatment under solar light
Leah Pandiscia, PhD
March 24, 2020
Herein we report for the first time the supramolecular hydrogelation of a derivative of 3-nitrotyrosine (3-NT), which is an oxidized… Continue reading Supramolecular Hydrogel from an Oxidized Byproduct of Tyrosine
Leah Pandiscia, PhD
March 24, 2020
Enzymatic gold nanoparticles (B-GNPs) have been synthesized using a natural anticancer agent bromelain (a cysteine protease) and these nanoparticles were… Continue reading Cisplatin bioconjugated enzymatic GNPs amplify the effect of cisplatin with acquiescence
Leah Pandiscia, PhD
March 24, 2020
HAX-1, a multifunctional protein involved in cell proliferation, calcium homeostasis, and regulation of apoptosis, is a promising therapeutic target. It… Continue reading Structural modeling and role of HAX-1 as a positive allosteric modulator of human serine protease HtrA2
Leah Pandiscia, PhD
March 24, 2020
Coat protein (COP) I and COP II complexes are involved in the transport of proteins between the endoplasmic reticulum and… Continue reading Lipid Binding Controls Dimerization of the Coat Protein p24 Transmembrane Helix
Leah Pandiscia, PhD
March 24, 2020
Stress-induced unfolding and fibrillation of insulin represent serious medical and biotechnological problems. Despite many attempts to elucidate the molecular mechanisms… Continue reading Modulating Insulin Fibrillation Using Engineered B-Chains with Mutated C-Termini
Leah Pandiscia, PhD
March 24, 2020
To investigate the interaction between bovine serum albumin (BSA) and silver nanoparticles (AgNPs) at five different pHs (below (3.0 and… Continue reading Influence of pH on interaction of silver nanoparticles – protein: Analyses by spectroscopic and thermodynamic ideology
Leah Pandiscia, PhD
March 24, 2020
Dengue virus (DENV) nonstructural 1 (NS1) protein is a specific and sensitive biomarker for the diagnosis of dengue. In this… Continue reading Development of peptide biosensor for the detection of dengue fever biomarker, nonstructural 1
Leah Pandiscia, PhD
March 24, 2020
Treatment of ocular diseases associated with neovascularization currently requires frequent intravitreal injections of antivascular endothelial growth factor (anti-VEGF) therapies. Reducing… Continue reading Hyaluronic Acid–Antibody Fragment Bioconjugates for Extended Ocular Pharmacokinetics
Leah Pandiscia, PhD
March 24, 2020
α-Linked GalNAc (α-GalNAc) is most notably found at the nonreducing terminus of the blood type–determining A-antigen and as the initial… Continue reading Prospecting for microbial α-N-acetylgalactosaminidases yields a new class of GH31 O-glycanase
Leah Pandiscia, PhD
March 24, 2020
A novel visible-light-driven Bi12O17Cl2/AgI composite was synthesized by a deposition-precipitation method at room temperature. Dispersing AgI on Bi12O17Cl2 substrate endows AgI… Continue reading Improving the stability and photocatalytic activity of AgI via constructing novel Bi12O17Cl2/AgI composite
Leah Pandiscia, PhD
March 24, 2020