Cytochrome b562 (Cyt b562) reconstituted with nickel didehydrocorrin (NiII(DDHC)), a protein-based functional model of methyl-coenzyme M reductase (MCR), was investigated to demonstrate methane… Continue reading Methane generation via intraprotein C–S bond cleavage in cytochrome b562 reconstituted with nickel didehydrocorrin
Leah Pandiscia, PhD
March 24, 2020
Azoreductase from Chromobacterium violaceum was characterized biophysically using experimental and computational tools. The in-silico docking and cross-linking experiments using glutaraldehyde suggest dimeric nature of… Continue reading Folding and stability of recombinant azoreductase enzyme from Chromobacterium violaceum
Leah Pandiscia, PhD
March 24, 2020
Leah Pandiscia, PhD
March 24, 2020
To evaluate the protease activity in dentin matrices subjected to lactic acid (LA) in comparison to polyacrylic acid (PAA) challenge… Continue reading Alternative model for cathepsin K activation in human dentin
Leah Pandiscia, PhD
March 24, 2020
Atrazine is a common herbicide that is widely used to control weed growth in both agricultural and residential settings. It… Continue reading In-Solution Molecular Recognition Comparison of Aptamers against the Herbicide Atrazine
Leah Pandiscia, PhD
March 24, 2020
By using the designed N-rich 3,6-bis(4-methyl-1H-imidazol-1-yl)pyridazine (b4mmp) and chiral d-camphoric acid (d-cam) ligands to react with cadmium acetate, a new bulk… Continue reading A Thermostable Three-Dimensional Homochiral Metal–Organic Framework Constructed from N-Rich Ligand: Syntheses, Crystal Structures, and Properties
Leah Pandiscia, PhD
March 24, 2020
Two new citrinin dimers named dicitrinones E and F (1 and 2), together with one biogenetically related known citrinin monomer (3), were… Continue reading Dicitrinones E and F, citrinin dimers from the marine derived fungus Penicillium citrinum HDN-152-088
Leah Pandiscia, PhD
June 29, 2020
Leah Pandiscia, PhD
March 24, 2020
Lytic polysaccharide monooxygenases (LPMOs) are copper-containing enzymes which promote the degradation of recalcitrant polysaccharides like cellulose or chitin. Here, we… Continue reading Thermal unfolding and refolding of a lytic polysaccharide monooxygenase from Thermoascus aurantiacus
Leah Pandiscia, PhD
March 24, 2020
Artificial tubular networks are promising structures for biomaterial applications because of their large surface areas. A tubular network was formed… Continue reading Tubular Network Formation by Mixing Amphiphilic Polypeptides with Differing Hydrophilic Blocks
Leah Pandiscia, PhD
March 24, 2020
Polyphenols are secondary plant metabolites, which have received much attention because of their potential health benefits. Silibinin (SIL) is a… Continue reading Intercalation of a flavonoid, silibinin into DNA base pairs: Experimental and theoretical approach
Leah Pandiscia, PhD
March 24, 2020
CD151 is an abundantly expressed eukaryotic transmembrane protein on the cell surface. It is involved in cell adhesion, angiogenesis and… Continue reading High Yield Expression of Recombinant CD151 in E. coli and a Structural Insight into Cholesterol Binding Domain
Leah Pandiscia, PhD
March 24, 2020
Leah Pandiscia, PhD
March 24, 2020
Leah Pandiscia, PhD
March 24, 2020
The construction of chiral porous materials for practical enantioseparation remains a great challenge. As chiral compounds might display a distinctive… Continue reading Effects of Rigid Conjugated Groups: Toward Improving Enantioseparation Performances of Chiral Porous Organic Polymers
Leah Pandiscia, PhD
March 24, 2020
Human phenylalanine hydroxylase (hPAH) hydroxylates L-phenylalanine (L-Phe) to L-tyrosine, a precursor for neurotransmitter biosynthesis. Phenylketonuria (PKU), caused by mutations in PAH that impair PAH… Continue reading Structure of full-length wild-type human phenylalanine hydroxylase by small angle X-ray scattering reveals substrate-induced conformational stability
Leah Pandiscia, PhD
March 24, 2020
A highly conserved 458PLSSMXP464 sequence in the small subunit (S-subunit) of an industrially important Bacillus licheniformis γ-glutamyltranspeptidase (BlGGT) was identified by sequence alignment. Molecular… Continue reading Mutational Analysis of a Highly Conserved PLSSMXP Sequence in the Small Subunit of Bacillus licheniformis γ-Glutamyltranspeptidase
Leah Pandiscia, PhD
March 24, 2020
The non-targeted action of fungicides leads to DNA damage of organisms, which causes several serious diseases such as cancer, behavioral… Continue reading Mechanistic Aspects of Fungicide-Induced DNA Damage: Spectroscopic and Molecular Dynamics Simulation Studies
Leah Pandiscia, PhD
March 24, 2020
Photo-responsive materials with good luminescence performance in solid state have received widespread attention. However, the reported luminescent photo-responsive systems exhibit… Continue reading An AIEgen-based luminescent photo-responsive system used as concealed anti-counterfeit material
Leah Pandiscia, PhD
March 24, 2020
Nanocrystalline AZrTi2O7 (A = Mg, Ca, Sr and Ba) system has been synthesized by an auto-ignited combustion technique. The structure of the system… Continue reading Synthesis and characterization of AZrTi2O7 (A = mg, ca, Sr and Ba) functional nanoceramics
Leah Pandiscia, PhD
March 24, 2020