New types of polymers composed of bithiophene condensed with disilacyclohexadiene rings and benzothiadiazole were prepared by the platinum-catalyzed dehydrogenative bissilylation.… Continue reading Synthesis and optical properties of polymers with bithiophene condensed with disilacyclohexadiene rings and benzothiadiazole
Leah Pandiscia, PhD
March 24, 2020
In this study we describe the synthesis and characterisation of a new hydrazone-based fluorescent compound that is able to selectively… Continue reading A novel adaptive fluorescent probe for cell labelling
Leah Pandiscia, PhD
March 24, 2020
Novel water-soluble 4-aminonaphthalimides were synthesised and their cellular fluorescent imaging, cytotoxicity and ability to induced apoptosis evaluated. The lead compound 1 was… Continue reading Aminonaphthalimide hybrids of mitoxantrone and amonafide as anticancer and fluorescent cellular imaging agents
Leah Pandiscia, PhD
March 24, 2020
Herein, we report the synthesis, molecular structures and bioevaluation of two different cationic copper(II) complexes with the third generation quinolone… Continue reading Copper(ii) complexes based on levofloxacin and 2N-donor ligands: synthesis, crystal structures and in vitro biological evaluation
Leah Pandiscia, PhD
March 24, 2020
The protein ALL1 fused from chromosome 1q (AF1q) is overexpressed in a variety of cancers and acts to activate several… Continue reading Recombinant expression and purification of AF1q and its interaction with T-cell Factor 7
Leah Pandiscia, PhD
March 24, 2020
The i-motif is a biologically relevant non-canonical DNA structure formed by cytosine-rich sequences. Despite the importance of the factors affecting… Continue reading Assessing the influence of pH and cationic strength on i-motif DNA structure
Leah Pandiscia, PhD
March 24, 2020
A fluorite-type compound, Pb0.35Bi0.65O1.59, was synthesized by a hydrothermal reaction. The crystal structure of the compound was refined using synchrotron… Continue reading Hydrothermal synthesis and crystal structure of a fluorite-type Pb0.35Bi0.65O1.59 compound with photocatalytic activity
Leah Pandiscia, PhD
March 24, 2020
Leah Pandiscia, PhD
March 24, 2020
Leah Pandiscia, PhD
March 24, 2020
Chiral separation is of critical importance in many areas spanning from pharmaceutics and agriculture to catalysis. Coordination polymers and metal–organic… Continue reading Enantioselective separation under humid conditions by chiral Hofmann clathrates: new opportunities for vintage materials
Leah Pandiscia, PhD
March 24, 2020
As part of our ongoing investigation of the bioactive constituents from the roots of Glycyrrhiza uralensis Fisch., seven new flavonoid glycosides (1–7)… Continue reading Seven new flavonoid glycosides from the roots of Glycyrrhiza uralensis and their biological activities
Leah Pandiscia, PhD
March 24, 2020
Two new harziane diterpene lactones, possessing a 6/5/7/5-fused carbocyclic core containing a lactone ring system, harzianelactones A and B (1 and 2),… Continue reading Potent Phytotoxic Harziane Diterpenes from a Soft Coral-Derived Strain of the Fungus Trichoderma harzianum XS-20090075
Leah Pandiscia, PhD
June 29, 2020
Hearing and balance rely on the transduction of mechanical stimuli arising from sound waves or head movements into electrochemical signals.… Continue reading Nanomechanics of tip-link cadherins
Leah Pandiscia, PhD
March 24, 2020
Leah Pandiscia, PhD
March 24, 2020
The prokaryotic βγ-crystallins are a large group of uncharacterized domains with Ca2+-binding motifs. We have observed that a vast number… Continue reading βγ-Crystallination Endows a Novel Bacterial Glycoside Hydrolase 64 with Ca2+-Dependent Activity Modulation
Leah Pandiscia, PhD
March 24, 2020
In this work, two different approaches have been developed to predict the food effect and the bioequivalence of marketed itraconazole… Continue reading Prediction of Bioequivalence and Food Effect Using Flux- and Solubility-Based Methods
Leah Pandiscia, PhD
March 24, 2020
Leah Pandiscia, PhD
March 24, 2020
Angiogenesis is a biological process finely tuned by a plethora of pro- and anti-angiogenic molecules, among which vascular endothelial growth… Continue reading Biochemical and Conformational Characterization of Recombinant VEGFR2 Domain 7
Leah Pandiscia, PhD
March 24, 2020
Leah Pandiscia, PhD
March 27, 2020
Leah Pandiscia, PhD
March 27, 2020