Holliday junctions (HJs) are four-way DNA structures that occur in DNA repair by homologous recombination. Specialized nucleases, termed resolvases, remove… Continue reading RuvC uses dynamic probing of the Holliday junction to achieve sequence specificity and efficient resolution
Leah Pandiscia, PhD
November 13, 2019
Antimicrobial peptides (AMPs), essential elements in host innate immune defenses against numerous pathogens, have received considerable attention as potential alternatives… Continue reading Conjugation of Cell-Penetrating Peptides to Antimicrobial Peptides Enhances Antibacterial Activity
Leah Pandiscia, PhD
November 13, 2019
Three new sesquiterpenoids (compounds 4, 5, and 26), along with 23 known sesquiterpenoids (compounds 1–3 and 6–25) and two diterpenoids (compounds 27 and 28), were obtained from Curcuma phaeocaulis, and… Continue reading STAT3-inhibitory activity of sesquiterpenoids and diterpenoids from Curcuma phaeocaulis
Leah Pandiscia, PhD
November 13, 2019
Leah Pandiscia, PhD
November 13, 2019
Tropomyosin is a coiled-coil actin binding protein key to the stability of actin filaments. In muscle cells, tropomyosin is subject to calcium regulation,… Continue reading Phospho-regulation of tropomyosin is crucial for actin cable turnover and division site placement.
Leah Pandiscia, PhD
November 13, 2019
Obg is a versatile GTPase that plays a pivotal role in bacterial persistence. We previously showed that the Escherichia coli homolog ObgE… Continue reading Biochemical determinants of ObgE‐mediated persistence
Leah Pandiscia, PhD
November 13, 2019
Protein–polymer bioconjugate self-assembly has attracted a great deal of attention as a method to fabricate protein nanomaterials in solution and… Continue reading Predicting Protein–Polymer Block Copolymer Self-Assembly from Protein Properties
Leah Pandiscia, PhD
November 13, 2019
LCI is a 47-residue antimicrobial peptide produced by Bacillus subtilis. The peptide displays potent activity against plant pathogens, Xanthomonas and Pseudomonas.… Continue reading Aromatic-rich C-terminal region of LCI is a potent antimicrobial peptide in itself
Leah Pandiscia, PhD
November 13, 2019
A novel aminoquinoline derivative (AQ) was synthesized and applied as a solvatochromic fluorescent probe to study proteins and their alterations. AQ is… Continue reading Novel aminoquinoline-based solvatochromic fluorescence probe: Interaction with albumin, lysozyme and characterization of amyloid fibrils
Leah Pandiscia, PhD
November 13, 2019
Leah Pandiscia, PhD
November 13, 2019
Leah Pandiscia, PhD
November 13, 2019
The Moebius topology (twisted, single-sided strip) is intriguing because of its structural elegance and distinct properties. Here we report the… Continue reading Moebius strips of chiral block copolymers
Leah Pandiscia, PhD
November 13, 2019
Noninvasive real-time biosensors to measure glucose levels in the body fluids have been widely investigated for continuous glucose monitoring of… Continue reading Hyaluronate–Gold Nanoparticle/Glucose Oxidase Complex for Highly Sensitive Wireless Noninvasive Glucose Sensors
Leah Pandiscia, PhD
November 13, 2019
A fluorometric method is described for the determination of ofloxacin (OFL). It is based on the use of the fluorescent… Continue reading Fluorometric determination for ofloxacin by using an aptamer and SYBR Green I
Leah Pandiscia, PhD
November 13, 2019
Transmembrane domains of membrane proteins sometimes contain conserved charged or ionizable residues which may be essential for protein function and… Continue reading Breaking the Backbone: Central Arginine Residues Induce Membrane Exit and Helix Distortions within a Dynamic Membrane Peptide
Leah Pandiscia, PhD
November 13, 2019
Leah Pandiscia, PhD
November 13, 2019
Leah Pandiscia, PhD
November 13, 2019
Leah Pandiscia, PhD
November 13, 2019
Honeybees communicate with members of their intra-species via pheromones. The volatile pheromones, β-ocimene and allo-ocimene, are the primary signals of… Continue reading Mechanistic insight into binding interaction between chemosensory protein 4 and volatile larval pheromones in honeybees (Apis mellifera)
Leah Pandiscia, PhD
November 13, 2019
Indium Sulfide (In2S3) is a promising candidate to replace Cadmium Sulfide (CdS) as a buffer layer in thin film solar… Continue reading Fabrication of visible light photodetector using co-evaporated Indium Sulfide thin films
Leah Pandiscia, PhD
November 13, 2019