The interactions of 6–8 ring hairpin polyamides (PAs) with the minor groove of DNA have been investigated extensively. More recent… Continue reading DNA binding thermodynamics and site stoichiometry as a function of polyamide size
Leah Pandiscia, PhD
November 13, 2019
A new prenylated benzophenone, hypatulin C (1), was isolated from the leaves of Hypericum patulum together with a biogenetically related analog, hypelodin… Continue reading Prenylated benzophenone derivatives from Hypericum patulum
Leah Pandiscia, PhD
November 13, 2019
Leah Pandiscia, PhD
November 13, 2019
In this study, we evaluated the adsorption of proteins to 2,2,6,6-tetramethylpiperidine-1-oxyl oxidized cellulose nanofibers (TOCNs) and their structures on the… Continue reading Structure retention of proteins interacting electrostatically with TEMPO-oxidized cellulose nanofiber surface
Leah Pandiscia, PhD
November 13, 2019
Polypeptides containing periodic aromatic residues in their main chains were synthesized via papain-catalyzed chemoenzymatic polymerization of tripeptide ester monomers under… Continue reading Periodic introduction of aromatic units in polypeptides via chemoenzymatic polymerization to yield specific secondary structures with high thermal stability
Leah Pandiscia, PhD
November 13, 2019
Five derivatives of cyano-containing 9-alkyl-9H-aza[7]helicene were synthesized and their behavior in the crystallization was investigated. Only one of the derivatives,… Continue reading Effect of the Position of the Cyano Group on Molecular Recognition, Supramolecular Superhelix Architecture, and Spontaneous Resolution of Aza[7]helicenes
Leah Pandiscia, PhD
November 13, 2019
Leah Pandiscia, PhD
November 13, 2019
Two new somatostatin analogs with a characteristic part of the sequence in their structures, -c(Cys-Phe-Trp-Lys-Thr-Cys)-, were synthesized and analyzed in… Continue reading The Analysis of the Structural Aspects of Cu (II) Binding by Cyclic His/Asp-Analogues of Somatostatin
Leah Pandiscia, PhD
November 13, 2019
The Sonogashira–Hagihara coupling polymerization of ferrocene‐containing l‐phenylalanine‐derived optically active o‐, m‐, p‐substituted bis(iodophenylene) monomers 1o , 1m , 1p with 1,4‐diethynylbenzene (2) and 1,4‐diethynyl‐2,5‐bis[2‐(2‐methoxyethoxy)ethoxy]benzene (3) is carried out to obtain… Continue reading Synthesis, Chiroptical, and Redox Properties of Ferrocene‐Containing Optically Active Polymers
Leah Pandiscia, PhD
November 13, 2019
Leah Pandiscia, PhD
November 13, 2019
Thioredoxin (Trx) is a conserved, cytosolic reductase in all known organisms. The enzyme receives two electrons from NADPH via thioredoxin… Continue reading Functional analyses of ancestral thioredoxins provide insights into their evolutionary history
Leah Pandiscia, PhD
November 13, 2019
Leah Pandiscia, PhD
November 13, 2019
To address the need to biodegradable, electroactive conduits accelerating nerve regeneration, here we develop a nanocomposite hydrogel made of alginate… Continue reading An electroactive alginate hydrogel nanocomposite reinforced by functionalized graphite nanofilaments for neural tissue engineering
Leah Pandiscia, PhD
November 13, 2019
Leah Pandiscia, PhD
November 13, 2019
Metallized DNA is an exciting functional material having widespread utility toward multifunctional applications. However, conventional DNA metallization processes are time-consuming… Continue reading Facile Process for Metallizing DNA in a Multitasking Deep Eutectic Solvent for Ecofriendly C–C Coupling Reaction and Nitrobenzene Reduction
Leah Pandiscia, PhD
June 29, 2020
Leah Pandiscia, PhD
November 13, 2019
Leah Pandiscia, PhD
November 13, 2019
MicroRNAs are a ubiquitous class of non-coding RNAs able to regulate gene expression in diverse biological processes. Widespread miRNAs deregulation… Continue reading A combined experimental and computational study on peptide nucleic acid (PNA) analogues of tumor suppressive miRNA-34a
Leah Pandiscia, PhD
November 13, 2019
Ovalbumin (OVA) is the major protein in egg white and has multiple functional properties. We prepared the covalent conjugate OVA–(−)-epigallo-catechin… Continue reading Function, digestibility and allergenicity assessment of ovalbumin–EGCG conjugates
Leah Pandiscia, PhD
November 13, 2019
Photomedicine-based antimicrobial therapy has emerged as an alternative treatment for antibiotic-resistant microbial infections. Although various photosensitizers (PSs) have been reported… Continue reading Porphyrin Functionalized Gelatin Nanoparticle-Based Biodegradable Phototheranostics: Potential Tools for Antimicrobial Photodynamic Therapy
Leah Pandiscia, PhD
November 13, 2019