Cyclodextrins are very important excipients in the pharmaceutical industry. Given the multitude of native and semisynthetic cyclodextrin derivatives, there is… Continue reading Simple circular dichroism method for selection of the optimal cyclodextrin for drug complexation
Leah Pandiscia, PhD
November 13, 2019
Chiral self‐assembly of peptides is of fundamental interest in the field of biology and material science. Protamine, an alkaline biomacromolecule… Continue reading Protamine‐induced condensation of peptide nanofilaments into twisted bundles with controlled helical geometry
Leah Pandiscia, PhD
November 13, 2019
Leah Pandiscia, PhD
June 29, 2020
We used wet chemical methods to fabricate CdSm/ZnSen type-II core/shell (C/S) quantum dots (QDs) doped with different Cu contents (x), where m is… Continue reading Tunable photoluminescent Cu-doped CdS/ZnSe type-II core/shell quantum dots
Leah Pandiscia, PhD
November 13, 2019
The DNA/RNA-binding KIN protein was discovered in 1989, and since then, it has been found to participate in several processes,… Continue reading Biophysical characterization and molecular phylogeny of human KIN protein
Leah Pandiscia, PhD
November 13, 2019
Chitin deacetylase, an enzyme isolated from Cryptococcus laurentii RY1, catalyzes the hydrolysis of acetamido group of N-acetyl-D-glucosamine unit of chitin. The primary objective… Continue reading DMSO strengthens chitin deacetylase-chitin interaction: Physicochemical, kinetic, structural and catalytic insights
Leah Pandiscia, PhD
November 13, 2019
The present study is focused on the binding interaction of sulfadoxine with bovine serum albumin under simulated physiological conditions using spectrofluorimetry. Various… Continue reading Spectral and molecular modelling studies of sulfadoxine interaction with bovine serum albumin
Leah Pandiscia, PhD
November 13, 2019
The human TRA2B gene consists of 10 exons and 9 introns and produces 5 splice isoforms (TRA2β1 to TRA2β5). TRA2B exon 2 encodes multiple premature termination… Continue reading HnRNPA1 interacts with G-quadruplex in the TRA2B promoter and stimulates its transcription in human colon cancer cells
Leah Pandiscia, PhD
November 13, 2019
In this work novel magnetic cationic liposomal nanoformulations were synthesized for the encapsulation of a crystallographically defined ternary V(IV)-curcumin-bipyridine (VCur)… Continue reading Magnetic cationic liposomal nanocarriers for the efficient drug delivery of a curcumin-based vanadium complex with anticancer potential
Leah Pandiscia, PhD
November 13, 2019
Peroxiredoxins (Prx) are enzymes that efficiently reduce hydroperoxides through active participation of cysteine residues (CP, CR). The first step in… Continue reading Unraveling the effects of peroxiredoxin 2 nitration; role of C-terminal tyrosine 193
Leah Pandiscia, PhD
November 13, 2019
Leah Pandiscia, PhD
November 13, 2019
Photoresponsive materials with good luminescence property in solid state have shown promising applications in bio-imaging, photo-patterning, and optical switch related… Continue reading Facile synthesis of a photoresponsive AIEgen used for monitoring UV light and photo-patterning
Leah Pandiscia, PhD
November 13, 2019
In this work, photo-sensitive core/shell nanoparticles (NPs) based on biocompatible dextran-g-poly(o-nitrobenzyl acrylate) copolymers (Dex-g-PNBA), containing dextran as hydrophilic backbone and… Continue reading Light-sensitive dextran-covered PNBA nanoparticles to continuously or discontinuously improve the drug release
Leah Pandiscia, PhD
November 13, 2019
Gallic acid is a naturally occurring plant polyphenol found in green tea and various fruits. Under certain conditions gallic acid… Continue reading Inactivation of Alpha-2-Macroglobulin by Photo-Illuminated Gallic Acid
Leah Pandiscia, PhD
November 13, 2019
Lonimacranaldes A and B (1 and 2), along with one biogenetically related intermediate, lonimacranalde C (3), were isolated from the flower buds… Continue reading Lonimacranaldes A–C, three iridoids with novel skeletons from Lonicera macranthoides
Leah Pandiscia, PhD
November 13, 2019
Metformin hydrochloride is an orally administered biguanide which is an oral anti-hyperglycemic agent. It shows incomplete absorption from the gastrointestinal… Continue reading An investigation on host-guest complexation of Metformin hydrochloride with hydroxypropyl-α-cyclodextrin for enhanced oral bioavailability
Leah Pandiscia, PhD
November 13, 2019
Leah Pandiscia, PhD
November 13, 2019
Chemiluminescent (CL) reagent N-(4-aminobutyl)-N-ethylisoluminol (ABEI)-functionalized CaCO3 microspheres with a dual catalytic system consisting of Co2+ and horseradish peroxidase (HRP) (HRP/ABEI/Co2+-CaCO3 MPs) were synthesized via… Continue reading Combined Transition-Metal/Enzyme Dual Catalytic System for Highly Intensive Glow-Type Chemiluminescence-Functionalized CaCO3 Microspheres
Leah Pandiscia, PhD
November 13, 2019
Obtaining the stable dispersion of single-walled carbon nanotubes is vital for realizing their practical applications. In our work, soy protein… Continue reading The effect of the secondary structures of proteins on dispersing SWNTs
Leah Pandiscia, PhD
November 13, 2019
Nucleic acid aptamers have emerged as an attractive class of carrier molecules due to their ability to bind with high… Continue reading RNA G-quadruplex as supramolecular carrier for cancer-selective delivery
Leah Pandiscia, PhD
November 13, 2019