Qualitative and quantitative understanding of partially folded states of protein is essential in gaining deeper insights into folding pathways. We… Continue reading Alkali induced unique partially folded state of bovine serum albumin: qualitative and quantitative insights
Leah Pandiscia, PhD
November 13, 2019
Lactoferrin (LF) is a multifunctional protein that plays important physiological roles as one of the most concentrated proteins in many… Continue reading Modification of lactoferrin by peroxynitrite reduces its antibacterial activity and changes protein structure
Leah Pandiscia, PhD
November 13, 2019
Nanoparticles (NPs) consisting of biodegradable and biocompatible polymers may have the ability to deliver a cargo to specific tissue, cell… Continue reading Oligonucleotide loaded polypeptide‐peptide nanoparticles towards mitochondrial‐targeted delivery
Leah Pandiscia, PhD
November 13, 2019
Fibrillation of supramolecular building blocks represents an important model system for complex proteins and peptides, such as amyloidogenic proteins, displaying… Continue reading Secondary structure of end group functionalized oligomeric-L-lysines: investigations of solvent and structure dependent helicity
Leah Pandiscia, PhD
November 13, 2019
The HIV-1 accessory protein Vpu mediates the downregulation of several host cell proteins, an activity that is critical for viral… Continue reading Hydrophobic matching of HIV-1 Vpu transmembrane helix-helix interactions is optimized for subcellular location
Leah Pandiscia, PhD
November 13, 2019
The chemical investigation of the wheat plant pathogen Parastagonospora nodorum SN15 led to the purification of seven highly oxygenated acetylenic cyclohexanoids named… Continue reading Highly oxygenated isoprenylated cyclohexanoids from the fungus Parastagonospora nodorum SN15
Leah Pandiscia, PhD
November 13, 2019
Leah Pandiscia, PhD
November 13, 2019
(Zn,Ni)(O,S) nanoparticles were uniformly deposited on nanoporous SiO2spheres to form SiO2@(Zn,Ni)(O,S) nanocomposites (NCs). To obtain optimum deposition of (Zn,Ni)(O,S) on… Continue reading Concept of Stagnant Capillarity Water in the Nanoporous SiO2@(Zn,Ni)(O,S) Nanocomposite Photocatalyst as a Strategy to Improve Hydrogen Evolution
Leah Pandiscia, PhD
November 13, 2019
Gamma secretase activating protein (GSAP) present in β-amyloid pathway orchestrates the formation of β-amyloid plaques by γ-secretase activation and is… Continue reading Tracing the GSAP–APP C-99 Interaction Site in the β-Amyloid Pathway Leading to Alzheimer’s Disease
Leah Pandiscia, PhD
November 13, 2019
In contrast to conventional dispersions of solid microspheres, dilute dispersions containing soft hydrogel microspheres (microgels) exhibit unique drying behavior due… Continue reading Effect of Charge Groups Immobilized in Hydrogel Microspheres during the Evaporation of Aqueous Sessile Droplets
Leah Pandiscia, PhD
November 13, 2019
Leah Pandiscia, PhD
November 13, 2019
Alzheimer’s disease is a chronic neurodegenerative disease characterized by the accumulation of pathological aggregates of amyloid beta peptide. Many efforts… Continue reading Inhibition of Aβ1–42 Fibrillation by Chaperonins: Human Hsp60 Is a Stronger Inhibitor than Its Bacterial Homologue GroEL
Leah Pandiscia, PhD
November 13, 2019
Protein aggregation has caused limitations in the study and development of protein-based biopharmaceuticals. We prepared different polysulfobetaine (poly-SPB) polymers via… Continue reading Comparative Study of Protein Aggregation Arrest by Zwitterionic Polysulfobetaines: Using Contrasting Raft Agents
Leah Pandiscia, PhD
November 13, 2019
The twin-ATPase ABCE1 has a vital function in mRNA translation by recycling terminated or stalled ribosomes. As for other functionally… Continue reading ABCE1 Controls Ribosome Recycling by an Asymmetric Dynamic Conformational Equilibrium
Leah Pandiscia, PhD
November 13, 2019
Titanium and its alloys especially Ti6Al4V have long been used in biomedical implants. Although, Ti6Al4V is biocompatible, yet there has… Continue reading Silk fibroin coated TiO2 nanotubes for improved osteogenic property of Ti6Al4V bone implants
Leah Pandiscia, PhD
November 13, 2019
Leah Pandiscia, PhD
November 13, 2019
The origin of terrestrial bioorganic homochirality is one of the most important and unresolved problems in the study of chemical… Continue reading Origin of Terrestrial Bioorganic Homochirality and Symmetry Breaking in the Universe
Leah Pandiscia, PhD
November 13, 2019
Anuran amphibian skin secretions are a rich source of peptides, many of which represent novel protease inhibitors and can potentially… Continue reading Discovery and Rational Design of a Novel Bowman-Birk Related Protease Inhibitor
Leah Pandiscia, PhD
November 13, 2019
In the present study, we investigate degradable anionic dendritic nanogels (DNG) as carriers for antimicrobial peptides (AMPs). In such systems,… Continue reading Degradable dendritic nanogels as carriers for antimicrobial peptides
Leah Pandiscia, PhD
November 13, 2019
A glycoside hydrolase family 5 (GH5) subfamily 22 gene, designated T81Xyl5_22A, was identified in the genome of the aerobic thermophilic… Continue reading A novel thermostable GH5 β-xylosidase from Thermogemmatispora sp. T81
Leah Pandiscia, PhD
November 13, 2019