Found 9617 Results / Page 190 of 481
2019 / JACS
The recently discovered Rrf2 family transcriptional regulator RsrR coordinates a [2Fe–2S] cluster. Remarkably, binding of the protein to RsrR-regulated promoter… Continue reading Crystal Structure of the Transcription Regulator RsrR Reveals a [2Fe–2S] Cluster Coordinated by Cys, Glu, and His Residues
2019 / Investigational New Drugs
Thiosemicarbazone is a class of compounds with potential applications in medicine, presenting high capacity to inhibit the growth of cancer… Continue reading In vitro and in vivo cytotoxic activity and human serum albumin interaction for a methoxy-styryl-thiosemicarbazone
2019 / Journal of Peptide Science
The placental growth factor (PlGF), a member of VEGF family, plays a crucial role in pathological angiogenesis, especially ischemia, inflammation,… Continue reading Short PlGF‐derived peptides bind VEGFR‐1 and VEGFR‐2 in vitro and on the surface of endothelial cells
2019 / Biomacromolecules
Nature has developed different protein mediated mechanisms to remodel cellular membranes. One of the proteins that is implicated in these… Continue reading Cooperation of helix insertion and lateral pressure to remodel membranes
2019 / Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics
Subcutaneous insulin delivery serves as the major treatment for the ever-increasing spread of type II diabetes worldwide. However, long-term exposure to insulin… Continue reading Sequence specificity of amylin-insulin interaction: a fragment-based insulin fibrillation inhibition study
2019 / Microbial Cell Factories
Pichia pastoris (syn. Komagataella phaffii) is one of the most highly utilized eukaryotic expression systems for the production of heterologous… Continue reading Recombinant O-mannosylated protein production (PstS-1) from Mycobacterium tuberculosis in Pichia pastoris (Komagataella phaffii) as a tool to study tuberculosis infection
2019 / The Journal of Physical Chemistry B
One of the most stable quadruplexes is formed by the G3T sequence (GGGTGGGTGGGTGGG) that folds into a parallel quadruplex with… Continue reading Stability Factors of the Parallel Quadruplexes: DNA Versus RNA
2019 / Organic Chemistry Frontiers
This paper reports the synthesis of a planar-chiral monohydroxy-functionalized pillar[5]arene amenable to a wide variety of chemical modifications. Chiral resolution… Continue reading Chiral discrimination of 2-heptlyaminium salt by planar-chiral monohydroxy-functionalized pillar[5]arenes
2019 / molecules
A metabolic conversion study on microbes is known as one of the most useful tools to predict the xenobiotic metabolism… Continue reading Biotransformed Metabolites of the Hop Prenylflavanone Isoxanthohumol
2019 / Nanomaterials
Dye wastewater is one of the most important problems to be faced and solved in wastewater treatment. However, the treatment… Continue reading Fabrication and Highly Efficient Dye Removal Characterization of Beta-Cyclodextrin-Based Composite Polymer Fibers by Electrospinning
2019 / Journal of Biological Inorganic Chemistry
In this work, we have studied the effect of Crotalus basiliscus snake venom on the redox reaction of myoglobin (Mb), and by… Continue reading Effect of Crotalus basiliscus snake venom on the redox reaction of myoglobin
2019 / Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics
Amyloid aggregation has been associated with numerous human pathological diseases. A recent study has demonstrated that silk fibroin intermittently endorses amyloidogenesis in vivo. In… Continue reading Modulation of aggregation of silk fibroin by synergistic effect of the complex of curcumin and β-cyclodextrin
2019 / New Journal of Chemistry
Lyotropic bicontinuous cubic (QII) phases have attracted increasing attention as nanostructured fluidic matrices for some bio-polymers including enzymes and DNA.… Continue reading Improvement of lipidic bicontinuous cubic phases by the addition of a zwitterion with strong hydration ability and kosmotropicity
2019 / Journal of Materials Chemistry B
Protein misfolding plays a critical role in the manifestation of amyloidosis type diseases. Therefore, understanding protein unfolding and the ability… Continue reading Detecting lysozyme unfolding via the fluorescence of lysozyme encapsulated gold nanoclusters
2019 / Scientific Reports
The mouse Major Urinary Proteins (MUPs) contain a conserved β-barrel structure with a characteristic central hydrophobic pocket that binds a… Continue reading Effects of point mutations in the binding pocket of the mouse major urinary protein MUP20 on ligand affinity and specificity
2019 / Advanced Functional Materials
The alteration in protein conformation not only affects the performance of its biological functions, but also leads to a variety… Continue reading Plasmon‐Enhanced Fluorescent Sensor based on Aggregation‐Induced Emission for the Study of Protein Conformational Transformation
2019 / mBio
A wide range of bacterial pathogens have been shown to form biofilms, which significantly increase their resistance to environmental stresses,… Continue reading Physical Determinants of Amyloid Assembly in Biofilm Formation
2019 / Physical Chemistry Chemical Physics
The G-quadruplex-forming telomeric sequence (TTAGGG)4TT was investigated by polarized Ultraviolet Resonance Raman Scattering (UVRR) at 266 nm. The presence of… Continue reading Crowding and conformation interplay on human DNA G-quadruplex by ultraviolet resonant Raman scattering
2019 / ACS Chemical Neuroscience
The aggregation of α-synuclein (α-Syn) has been implicated strongly in Parkinson’s disease (PD). The intrinsically disordered nature of α-Syn makes… Continue reading Modulation of α-Synuclein Aggregation by Cytochrome c Binding and Hetero-dityrosine Adduct Formation
2019 / International Journal of Biological Macromolecules
The molecular interactions between two single-chain lysosomotropic surfactants DMM-11 (2-Dodecanoyloxyethyl)trimethylammonium bromide) and DMPM-11 (2-Dodecanoyloxypropyl)trimethylammonium bromide) with a small heme-protein(cytochrome c (cyt-c)) in Hepes buffer (pH = 7.4)… Continue reading Biomolecular interactions of lysosomotropic surfactants with cytochrome c and its effect on the protein conformation: A biophysical approach
