Found 9617 Results / Page 195 of 481
2018 / ACS Omega
In this paper, we present a new synthetic route to produce optically active nanofibers of poly[2-(sec-butyl) aniline] (PSBA). Optically active… Continue reading Optically Active Poly[2-(sec-butyl)aniline] Nanofibers Prepared via Enantioselective Polymerization
2018 / Journal of Biological Chemistry
Small heat-shock proteins (sHsps) are ubiquitous molecular chaperones, and sHsp mutations or altered expression are linked to multiple human disease… Continue reading It takes a dimer to tango: Oligomeric small heat shock proteins dissociate to capture substrate
2018 / The Journal of Physical Chemistry B
Vibrational circular dichroism (CD) and IR spectra of dichloromethane solutions of l-stercobilin and d-urobilin hydrochlorides have been recorded in the mid-IR region.… Continue reading l-Stercobilin-HCl and d-Urobilin-HCl. Analysis of Their Chiroptical and Conformational Properties by VCD, ECD, and CPL Experiments and MD and DFT Calculations
2019 / International Immunopharmacology
The oral route is one of the most convenient routes for drug and/or vaccine delivery. Yet variable nature of gastrointestinal tract due… Continue reading Chylomicron mimicking solid lipid nanoemulsions encapsulated enteric minicapsules targeted to colon for immunization against hepatitis B
2018 / CrystEngComm
The self-assembly of N- and C-protected tripeptides, Boc-Gly-Phe-Phe-OMe (1) and its analog Boc-Gly-Phg-Phe-OMe (2, Phg = phenylglycine), has been investigated.… Continue reading Unique crystallographic signatures of Boc-Gly-Phe-Phe-OMe and Boc-Gly-Phg-Phe-OMe and their self-association
2018 / International Journal of Molecular Sciences
SOUL, a heme-binding protein-2 (HEBP-2), interacts with apoptosis-linked gene 2 protein (ALG-2) in a Ca2+-dependent manner. To investigate the properties… Continue reading Thermodynamic Characterization of the Ca2+-Dependent Interaction Between SOUL and ALG-2
2018 / JACS
The synthesis of chiral polyoxometalates (POMs) is a challenge because of the difficulty to induce the formation of intrin-sically chiral… Continue reading Stereoselective Assembly of Gigantic Chiral Molybdenum Blue Wheels Using Lanthanide ions and Amino Acids
2018 / Advanced Healthcare Materials
Oral delivery of peptide/protein drugs has attracted worldwide attention due to its good patient compliance and convenience of administration. Orally… Continue reading Protein Corona Liposomes Achieve Efficient Oral Insulin Delivery by Overcoming Mucus and Epithelial Barriers
2018 / molecules
The carbazole ligand 3 was synthesized, characterized and its binding interactions with human telomeric (22HT) G-quadruplex DNA in Na+ and K+-containing buffer were… Continue reading Binding Study of the Fluorescent Carbazole Derivative with Human Telomeric G-Quadruplexes
2018 / Nanoscale
Recent studies have shown that antimicrobial peptides (AMPs) can self-assemble into supramolecular structures, but this has been overlooked as causative… Continue reading Self-assembly dynamics and antimicrobial activity of all L- and D-amino acid enantiomers of a designer peptide
2019 / Phytochemistry Letters
Two new Lycopodium alkaloids, phlenumdines D (1) and E (2), have been isolated from the club moss Phlegmariurus nummulariifolius (Blume) Ching along with ten… Continue reading Phlenumdines D and E, new Lycopodium alkaloids from Phlegmariurus nummulariifolius, and their regulatory effects on macrophage differentiation during tumor development
2019 / Biochemistry and Biophysics Reports
We tested whether a short model peptide derived from a group 3 late embryogenesisabundant (G3LEA) protein is able to maintain the fluorescence activity… Continue reading A LEA model peptide protects the function of a red fluorescent protein in the dry state
2019 / Biochemical and Biophysical Research Communications
The effect on protein conformation and thermal stability was studied for β-Galactosidase (β-Gal) encapsulated in the nanopores of a silicate matrix (Eβ-Gal). Circular dichroism spectra showed that, compared… Continue reading β-sheet to α-helix conversion and thermal stability of β-Galactosidase encapsulated in a nanoporous silica gel
2018 / Journal of Medicinal Chemistry
Here we describe the three-dimensional structure and antimicrobial mechanism of mBjAMP1, an antimicrobial peptide (AMP) isolated from Branchiostoma japonicum. The structure… Continue reading Structural and Functional Assessment of mBjAMP1, an Antimicrobial Peptide from Branchiostoma japonicum, Revealed a Novel α-Hairpinin-like Scaffold with Membrane Permeable and DNA Binding Activity
2018 / Biomacromolecules
The size control of nanomedicines for tumor diagnosis and therapy is of high importance, since it enables or disables deep… Continue reading Impact of Branching on the Solution Behavior and Serum Stability of Starlike Block Copolymers
2019 / RSC Advances
μ-Conotoxin PIIIA, a peptide toxin isolated from Conus purpurascens, blocks the skeletal muscle voltage-gated sodium channel NaV1.4 with significant potency. PIIIA… Continue reading Role of the disulfide bond on the structure and activity of μ-conotoxin PIIIA in the inhibition of NaV1.4
2019 / Solid State Nuclear Magnetic Resonance
Cellulose nanocrystal films with either disordered or chiral nematic structures of varying helical pitch were investigated using 23Na solid-state nuclear magnetic resonance (NMR)… Continue reading Solid-state 23Na NMR spectroscopy studies of ordered and disordered cellulose nanocrystal films
2019 / Phytochemistry Letters
Two new bisabolane-type sesquiterpenoids, (3R,4S,5R,7S)-3,4,5-trihydroxybisabola-10-ene-9-one (1), (1R,2S,5R,7R,8S)-2,8-epoxy-5-hydroxybisabola-3,10-diene-9-one (2), together with seven known anologues (3–9), were isolated from the cooking liquid… Continue reading Two new bisabolane-type sesquiterpenoids from the cooking liquid of Curcuma longa rhizomes
2018 / ACS Applied Polymer Materials
A new highly conjugated polymer–bioconjugate poly[9,9-bis(6′-adenine) hexyl)fluorene-co-4,7-(2,1,3 benzothiadiazole)] (PFBT-A) is developed using the well-known Pd(PPh3)4-catalyzed Suzuki cross-coupling polymerization reaction with… Continue reading Polyfluorene-Based Bioconjugates for Selective Detection of Ferritin in Normal and Cancer Human Blood Serums
2018 / Nucleic Acids Research
Poly (ADP-ribose) polymerase 1 (PARP1) has emerged as an attractive target for cancer therapy due to its key role in… Continue reading Structure of a (3+1) hybrid G-quadruplex in the PARP1 promoter
