Excess accumulation of collagen (fibrosis) undergoes self-aggregation, which leads to fibrillar collagen, on the extracellular matrix is the hallmark of… Continue reading Disintegration of collagen fibrils by Glucono-δ-lactone: An implied lead for disintegration of fibrosis
Leah Pandiscia, PhD
August 13, 2018
Multi-functional phenolic emulsifiers were prepared by covalently coupling β-Lactoglobulin (βLg) to caffeic acid (CA) using crosslinker chemistry at different pH… Continue reading Adding functionality to milk-based protein: Preparation, and physico-chemical characterization of β-lactoglobulin-phenolic conjugates
Leah Pandiscia, PhD
August 13, 2018
Leah Pandiscia, PhD
August 13, 2018
Polylactide (PLA) particles become increasingly important for practical applications as typical sustainable polymeric materials; however, their preparation still remains as… Continue reading Ring opening precipitation polymerization for preparing polylactide particles with tunable size and porous structure and their application as chiral material
Leah Pandiscia, PhD
August 13, 2018
Leah Pandiscia, PhD
August 13, 2018
Channel catfish skin is a by-product from catfish fillet production. Collagens were extracted from catfish skins by: (1) acid; (2)… Continue reading Isolation and characterization of collagen extracted from channel catfish (Ictalurus punctatus) skin
Leah Pandiscia, PhD
August 13, 2018
Reactions of monoanionic bidentate ligands 5-methylsalicylaldehyde (5-msal), 5-bromosalicylaldehyde (5-brsal), 5-nitrosalicylaldehyde (5-nsal) and 2-hydroxy-1-naphthaldehyde (2-hnap) with nickel perchlorate hexahydrate produced nickel(II)… Continue reading Investigation on biomolecular interactions of nickel(II) complexes with monoanionic bidentate ligands
Leah Pandiscia, PhD
August 13, 2018
Owing to the urine concentrating mechanism of kidney cells, urea concentration is very high (3.0–5.0 M) in mammalian kidneys which may denature many… Continue reading Counteraction of the deleterious effects of urea on structure and stability of mammalian kidney proteins by osmolytes
Leah Pandiscia, PhD
August 13, 2018
Leah Pandiscia, PhD
August 13, 2018
ricexip, a xylanase-inhibiting protein (XIP)-type gene, was expressed in Escherichia coli BL21 (DE3). The recombinant protein, reEriceXIP significantly inhibited catalytic activity of… Continue reading Inhibiting the Catalytic Activity of Family GH11 Xylanases by Recombinant Rice Xylanase-Inhibiting Protein
Leah Pandiscia, PhD
August 13, 2018
Activation of Wnt signaling induces Connexin43 (Cx43) expression via the transcriptional activity of β-catenin, and results in the enhanced accumulation… Continue reading Connexin43 Carboxyl-Terminal Domain Directly Interacts with β-Catenin
Leah Pandiscia, PhD
August 13, 2018
Polyacetylenes substituted with phenyl, N-tert-butoxycarbonyl-L-valine 4-anilide, and (S)-1-(acetoxy)ethyl groups with number-average molecular weights ranging from 3800 to 13 500 were synthesized by… Continue reading Synthesis of block copolymers using end-functionalized polyacetylenes as macroinitiators
Leah Pandiscia, PhD
August 13, 2018
The RGG domain, defined as closely spaced Arg-Gly-Gly repeats, is a DNA and RNA-binding domain in various nucleic acid-binding proteins.… Continue reading G-quadruplex binding ability of TLS/FUS depends on the β-spiral structure of the RGG domain
Leah Pandiscia, PhD
August 13, 2018
Electron transfer (ET) reactions via helical peptides composed of –(Aib-Pro)n– were studied in self-assembled monolayers and compared with –(Ala-Aib)n– peptides. Short Aib-Pro… Continue reading Effect of oscillation dynamics on long-range electron transfer in a helical peptide monolayer
Leah Pandiscia, PhD
August 13, 2018
Ligand-induced chirality in semiconductor nanocrystals (NCs) has attracted attention because of the tunable optical properties of the NCs. Induced circular… Continue reading Optically Active CdSe-Dot/CdS-Rod Nanocrystals with Induced Chirality and Circularly Polarized Luminescence
Leah Pandiscia, PhD
August 13, 2018
DNA and RNA guanine-rich oligonucleotides can form non-canonical structures called G-quadruplexes or “G4” that are based on the stacking of… Continue reading RNA synthesis is modulated by G-quadruplex formation in Hepatitis C virus negative RNA strand
Leah Pandiscia, PhD
August 13, 2018
Intrinsically disordered regions (IDRs) in proteins are highly abundant, but they are still commonly viewed as long stretches of polar,… Continue reading Protein Regulation by Intrinsically Disordered Regions: A Role for Subdomains in the IDR of the HIV‐1 Rev Protein
Leah Pandiscia, PhD
August 13, 2018
We report time-resolved measurements of the coupled protein–water modes of solvated ubiquitin during protein folding. Kinetic terahertz absorption (KITA) spectroscopy… Continue reading Hydrophobic Collapse of Ubiquitin Generates Rapid Protein–Water Motions
Leah Pandiscia, PhD
August 13, 2018
Understanding the process of chiral symmetry breaking, amplification, and transfer to the macroscopic chirality in the self-assembled system has been… Continue reading Symmetry Breaking and Amplification in a Self-Assembled Helix from Achiral trans-3-Nitrocinnamic Acid
Leah Pandiscia, PhD
August 13, 2018
Leah Pandiscia, PhD
August 13, 2018