Dementia with Lewy bodies (DLB), Parkinson’s disease (PD) and multiple system atrophy are characterized by the deposition of disease-associated α-synuclein. In the present… Continue reading Intracellular processing of disease-associated α-synuclein in the human brain suggests prion-like cell-to-cell spread
Leah Pandiscia, PhD
May 22, 2018
Leah Pandiscia, PhD
May 22, 2018
The title water-soluble thiol-capped QDs (quantum dots) were synthesized by reacting CdCl2, DMPS and NaHTe in a water medium [DMPS… Continue reading Synthesis, characterization and in vitro toxicity assessment of DMPS-capped CdTe quantum dots
Leah Pandiscia, PhD
May 22, 2018
A simple colorimetric and turn-on fluorescence receptor 1 was prepared and its cations and anions sensing properties were investigated in CH3CN solution.… Continue reading Discriminating detection between F− and CN− by naked eye from Schiff base sensor
Leah Pandiscia, PhD
May 22, 2018
Calcium zinc borophosphate glasses (CaZnBP) doped with various concentrations of Mn2+ ions and borate and phosphate as variable were prepared using… Continue reading Structural and luminescence properties of Mn2+ ions doped calcium zinc borophosphate glasses
Leah Pandiscia, PhD
May 22, 2018
Leah Pandiscia, PhD
May 22, 2018
Leah Pandiscia, PhD
May 22, 2018
Three new sesquiterpenoids (sinuketal (1), sinulins A and B (2 and 3)) and two new cembranoids (sinulins C and D (4 and 5)), as… Continue reading Terpenoids from the Soft Coral Sinularia sp. Collected in Yongxing Island
Leah Pandiscia, PhD
May 22, 2018
The first amphibian skin secretion-derived Bowman-Birk type chymotrypsin inhibitor is described here from the Asian green frog, Hylarana erythraea, and was… Continue reading A Bowman-Birk type chymotrypsin inhibitor peptide from the amphibian, Hylarana erythraea
Leah Pandiscia, PhD
May 22, 2018
Polymyxins, a family of cationic antimicrobial cyclic peptides, act as a last line of defense against severe infections by Gram-negative… Continue reading An Evolutionarily Conserved Mechanism for Intrinsic and Transferable Polymyxin Resistance
Leah Pandiscia, PhD
May 22, 2018
The unique biological features of supramolecular DNA have led to an increasing interest in biomedical applications such as biosensors. We… Continue reading Reversible Redox Activity by Ion-pH Dually Modulated Duplex Formation of i-Motif DNA with Complementary G-DNA
Leah Pandiscia, PhD
May 22, 2018
Leah Pandiscia, PhD
May 22, 2018
A chemical investigation of the ascomycetes of Daldinia concentrica was performed using silica gel column chromatography, ODS column chromatography, and preparative HPLC.… Continue reading Isoindolinones, Phthalides, and a Naphthoquinone from the Fruiting Body of Daldinia concentrica
Leah Pandiscia, PhD
May 22, 2018
The exceptional toxicity of botulinum neurotoxins (BoNTs) is mediated by high avidity binding to complex polysialogangliosides and intraluminal segments of… Continue reading A lipid-binding loop of botulinum neurotoxin serotypes B, DC and G is an essential feature to confer their exquisite potency
Leah Pandiscia, PhD
May 22, 2018
Polyethyleneimine (PEI) complexed with chiral D- (or L-) tartaric acid (tart) in water can self-organize into chiral and crystalline PEI/tart assemblies. It… Continue reading Convenient chirality transfer from organics to titania: construction and optical properties
Leah Pandiscia, PhD
May 22, 2018
Binding of recombinant prion protein with small highly structured RNAs, prokaryotic and eukaryotic prion protein mRNA pseudoknots, tRNA and polyA… Continue reading A quantitative characterization of interaction between prion protein with nucleic acids
Leah Pandiscia, PhD
May 22, 2018
Leah Pandiscia, PhD
May 22, 2018
Proline and valine exist in repetitive motifs in various structural proteins and play an important role in their physiological functions.… Continue reading Chemoenzymatic synthesis of polypeptides consisting of periodic di- and tri-peptide motifs similar to elastin
Leah Pandiscia, PhD
May 22, 2018
Leah Pandiscia, PhD
May 22, 2018
Biological feedback mechanisms exert precise control over the initiation and termination of molecular self-assembly in response to environmental stimuli, while… Continue reading Force and time-dependent self-assembly, disruption and recovery of supramolecular peptide amphiphile nanofibers
Leah Pandiscia, PhD
May 22, 2018