A seires of double-network cryogels (DNCs) were prepared from oligoethylene glycol (OEG)-based dendronized copolymer as the first network and polyvinyl… Continue reading Thermoresponsive double network cryogels from dendronized copolymers showing tunable encapsulation and release of proteins
Leah Pandiscia, PhD
May 22, 2018
Blue-light-regulated phosphodiesterase 1 (BlrP1) is a blue light sensor protein that controls the hydrolysis of cyclic dimeric guanosine monophosphate, which… Continue reading Photoreaction of BlrP1: a role of nonlinear photo-intensity sensor
Leah Pandiscia, PhD
May 22, 2018
Leah Pandiscia, PhD
May 22, 2018
Synthetic peptides containing the arginine–glycine–aspartate (RGD) motif have been used extensively as inhibitors of integrin–ligand interactions in studies of cell… Continue reading RAFT polymerization of a RGD peptide-based methacrylamide monomer for cell adhesion
Leah Pandiscia, PhD
May 22, 2018
The Sonogashira–Hagihara coupling polymerization of a D-hydroxyphenylglycine-derived diiodoarylene monomer and platinum-containing diethynylphenylene monomers with various substituents, HC[triple bond, length as m-dash]C–C6H4–C[triple… Continue reading Effect of phosphine ligand on the optical absorption/emission properties of platinum-containing conjugated polymers
Leah Pandiscia, PhD
May 22, 2018
Nanoparticles have been recognized as promising tools for targeted drug-delivery and protein therapeutics. However, the mechanisms of protein-nanoparticle interaction and… Continue reading Luminescent and paramagnetic properties of nanoparticles shed light on their interactions with proteins
Leah Pandiscia, PhD
May 22, 2018
Cationic surfactant cetyltrimethylammonium bromide (CTAB) and cetylpyridinium bromide (CPB) bind to the calf thymus DNA (ct-DNA) like anionic biopolymers electrostatically,… Continue reading Ratiometric Interactions of Anionic Surfactants with Calf Thymus DNA Bound Cationic Surfactants: Study II
Leah Pandiscia, PhD
May 22, 2018
New bis-2(5H)-furanone derivatives containing a benzidine core were synthesized via a one-step transition-metal-free reaction of benzidine with 5-substituted 3,4-dihalo-2(5H)- furanones. Their antitumor… Continue reading Bis-2(5H)-furanone Derivatives as New Anticancer Agents: Design, Synthesis, Biological Evaluation and Mechanism Studies
Leah Pandiscia, PhD
May 22, 2018
Herein, the influence of an amino acid side chain on the structural and functional properties of hydrogels has been described.… Continue reading The role of aromatic side chains on the supramolecular hydrogelation of naphthalimide/dipeptide conjugates
Leah Pandiscia, PhD
May 22, 2018
Leah Pandiscia, PhD
May 22, 2018
Leah Pandiscia, PhD
May 22, 2018
Conserpin is an engineered protein that represents the consensus of a sequence alignment of eukaryotic serpins: protease inhibitors typified by… Continue reading Probing the folding pathway of a consensus serpin using single tryptophan mutants
Leah Pandiscia, PhD
May 22, 2018
Amyloids are protein fibrils with a characteristic spatial structure. Amyloids were long perceived as the pathogens involved in a set… Continue reading M60-like metalloprotease domain of the Escherichia coli YghJ protein forms amyloid fibrils
Leah Pandiscia, PhD
May 22, 2018
Ahmpatinin iBu (1) and statinin iBu (2), two new linear peptides, a novel pyrrolidine derivative, (−)-(S)-2-[3-(6-methylheptanamido)-2-oxopyrrolidin-1-yl] acetic acid (3), and three known… Continue reading Ahmpatinin iBu, a new HIV-1 protease inhibitor, fromStreptomyces sp. CPCC 202950
Leah Pandiscia, PhD
May 22, 2018
Conducting hydrogels provide great potential for creating designer shape-morphing architectures for biomedical applications owing to their unique solid–liquid interface and… Continue reading Self-Assembly of Enzyme-Like Nanofibrous G-Molecular Hydrogel for Printed Flexible Electrochemical Sensors
Leah Pandiscia, PhD
May 22, 2018
Two new compounds, robillafuran and (+)-robillapyrone, were isolated from the culture extract of a fungal strain of Robillarda along with (+)-monascuspyrone. The… Continue reading Two new secondary metabolites from a fungus of the genus Robillarda
Leah Pandiscia, PhD
May 22, 2018
Chiral amplification in molecular self-assembly has profound impact on the recognition and separation of chiroptical materials, biomolecules, and pharmaceuticals. An… Continue reading Elucidation of the origin of chiral amplification in discrete molecular polyhedra
Leah Pandiscia, PhD
May 22, 2018
We report several DNA nanodevices monitored with fluorogenic looped-out 2-aminopurine. It is found that looped-out 2-AP, an analogue of adenine,… Continue reading DNA nanodevices monitored with fluorogenic looped-out 2-aminopurine
Leah Pandiscia, PhD
May 22, 2018
Nickel(II) and zinc(II) complexes of the 19–22 peptide fragments of rat amylin were studied by potentiometric, UV-vis, CD and NMR… Continue reading Complex formation of nickel(II) and zinc(II) ions with peptide fragments of rat amylin
Leah Pandiscia, PhD
May 22, 2018
In this study, a light-responsive multienzyme complex (GOx&hemin@PepM) was developed by incorporating glucose oxidase (GOx) and hemin within a peptide-based… Continue reading A light-responsive multienzyme complex combining cascade enzymes within a peptide-based matrix
Leah Pandiscia, PhD
May 22, 2018