Natural peptides are emerging as a leading alternative to conventional drugs and antibiotics, owing to their remarkable potency, better stability… Continue reading Antibacterial Natural Peptide Fractions from Indian Ganoderma lucidum
Leah Pandiscia, PhD
May 22, 2018
Phytochemical investigation of the alkaloid extract of Palicourea sessilis by LC-HRMS/MS using molecular networking and an in silico MS/MS fragmentation approach suggested… Continue reading Targeted Isolation of Monoterpene Indole Alkaloids from Palicourea sessilis
Leah Pandiscia, PhD
May 22, 2018
Three new isocyanoditerpenes (5–7) have been characterized from Australian specimens of the nudibranch Phyllidiella pustulosa. The planar structure and (3R,6S,7R) absolute… Continue reading Catalyst-Controlled Stereoselective Synthesis Secures the Structure of the Antimalarial Isocyanoterpene Pustulosaisonitrile-1
Leah Pandiscia, PhD
May 22, 2018
Four new neolignans, (E)-3-(hydroxymethyl)-2-(4-hydroxyphenyl)-5-(prop-1-en-1-yl)benzofuran-6-ol (1), methyl (E)-6-hydroxy-2-(4-hydroxyphenyl)-5-(prop-1-en-1-yl)benzofuran-3-carboxylate (2), (R)-4-hydroxy-3-(1-(4-hydroxyphenyl)propan-2-yl)benzaldehyde (3) and methyl (E,R)-3-(4-hydroxy-3-(1-(4-hydroxyphenyl)propan-2-yl)phenyl)acrylate (4) were isolated from the seeds of Daphniphyllum… Continue reading Cytotoxic neolignans from the traditional Chinese medicine Daphniphyllum macropodum Miq.
Leah Pandiscia, PhD
May 22, 2018
In this work, we have successfully prepared chiral carbon dots from chiral precursors. We prepared a few D-carbon dots using D-methionine, D-glucose, D-glucosamine, and L-carbon… Continue reading Chiral carbon dots and their effect on the optical properties of photosensitizers
Leah Pandiscia, PhD
May 22, 2018
The production and availability of enantiomerically pure compounds that spurred the development of chiral technologies and materials are very important… Continue reading Coordinative Alignment of Chiral Molecules to Control over the Chirality Transfer in Spontaneous Resolution and Asymmetric Catalysis
Leah Pandiscia, PhD
May 22, 2018
The quantitative interaction of soybean selenoprotein (SSP) with caffeine (CAF) has been studied by fluorescence, cyclic voltammetry and resonance Rayleigh… Continue reading Characterization of the Interaction Between Caffeine and Soybean Selenoprotein by Spectroscopic and Cyclic Voltammetric Methods
Leah Pandiscia, PhD
May 22, 2018
Antimicrobial peptides as part of the mammalian innate immune system target and remove major bacterial pathogens, often through irreversible damage… Continue reading Structural remodeling and oligomerization of human cathelicidin on membranes suggest fibril-like structures as active species
Leah Pandiscia, PhD
May 22, 2018
A series of [7]helicene and [7]helicene-like compounds composed of a cyclopenta[1,2-b:4,3-b′]dithiophene or dithieno[2,3-b:3′,2′-d]heterole moiety and two naphthalene moieties were successfully… Continue reading Synthesis and properties of [7]helicene and [7]helicene-like compounds with a cyclopenta[1,2-b:4,3-b′]dithiophene or dithieno[2,3-b:3′,2′-d]heterole skeleton
Leah Pandiscia, PhD
May 22, 2018
The electrodynamics of metals is well understood within the Drude conductivity model; properties of insulators and semiconductors are governed by… Continue reading Observation of dielectric universalities in albumin, cytochrome C and Shewanella oneidensis MR-1 extracellular matrix
Leah Pandiscia, PhD
May 22, 2018
Leah Pandiscia, PhD
May 22, 2018
Droplet-based microfluidics is an emerging technique that is capable of producing sophisticated supramolecular microcapsules in one step. However, food materials,… Continue reading Microfluidic fabrication of hollow protein microcapsules for rate-controlled release
Leah Pandiscia, PhD
May 22, 2018
The nature of the initial structural events during the base-induced unfolding of the native (N) state of proteins is poorly… Continue reading A dry molten globule-like intermediate during the base-induced unfolding of a multidomain protein
Leah Pandiscia, PhD
May 22, 2018
Previous work suggested that hemoglobin (Hb) tetramer formation slows autoxidation and hemin loss and that the naturally occurring mutant, Hb… Continue reading Engineering Oxidative Stability in Human Hemoglobin based on the Hb Providence (βK82D) mutation and Genetic Crosslinking
Leah Pandiscia, PhD
May 22, 2018
Leah Pandiscia, PhD
May 22, 2018
The acid lability of aliphatic ketals, which often serve as protection groups for 1,2-diols, is influenced by their local structural… Continue reading Scaling the Amphiphilic Character and Antimicrobial Activity of Gramicidin S by Dihydroxylation or Ketal Formation
Leah Pandiscia, PhD
May 22, 2018
Isotopically labeled enzymes (denoted as “heavy” or “Born–Oppenheimer” enzymes) have been used to test the role of protein dynamics in… Continue reading Protein Mass Effects on Formate Dehydrogenase
Leah Pandiscia, PhD
May 22, 2018
Leah Pandiscia, PhD
May 22, 2018
Nature utilizes optimally organized pigments in light-harvesting complexes. To mimic the natural photosynthetic proteins, effective control over inter-pigment interactions is… Continue reading Control of porphyrin interactions viastructural changes of a peptoid scaffold
Leah Pandiscia, PhD
May 22, 2018
Ohmic heating is a technique that has gained increasing attention because of its capacity to produce uniform heating, and claimed… Continue reading Cold gel-like emulsions of lactoferrin subjected to ohmic heating
Leah Pandiscia, PhD
May 22, 2018