Herein, the interaction between caffeic acid (CA), a hydroxycinnamic acid with favorable health impacts through the prevention of degenerative pathologies,… Continue reading Complex interaction of caffeic acid with bovine serum albumin: calorimetric, spectroscopic and molecular docking evidence
Leah Pandiscia, PhD
May 22, 2018
Leah Pandiscia, PhD
May 22, 2018
Leah Pandiscia, PhD
May 22, 2018
Collagen hybridizing peptides (CHP) have been demonstrated as a powerful vehicle for targeting denatured collagen (dColl) produced by disease or… Continue reading Self-Assembled Water-Soluble Nanofibers Displaying Collagen Hybridizing Peptides
Leah Pandiscia, PhD
May 22, 2018
The duplex and G-quadruplex DNA-binding of six nickel(II) and zinc(II) complexes of three salphen-like ligands (salphen = N,N′-bis-salicylidene-1,2-phenylenediaminato) was investigated by UV–visible… Continue reading The interaction of Schiff Base complexes of nickel(II) and zinc(II) with duplex and G-quadruplex DNA
Leah Pandiscia, PhD
May 22, 2018
Herein, we report a conjugation strategy, where we utilize a poly(ethylene oxide) cylindrical molecular brush architecture to design a self-assembled… Continue reading Thermal Stabilization of Enzymes with Molecular Brushes
Leah Pandiscia, PhD
May 22, 2018
A photoresponsive poly(o-nitrobenzyloxycarbonyl-L-lysine)-b-PEO (PNBL-b-PEO) polypeptide copolymer was synthesized and its photosensitive cleavage and self-assembly were monitored by means of UV-vis… Continue reading Photosensitive poly(o-nitrobenzyloxycarbonyl-L-lysine)-b-PEO polypeptide copolymers: synthesis, multiple self-assembly behaviors, and the photo/pH-thermo-sensitive hydrogels
Leah Pandiscia, PhD
May 22, 2018
Leah Pandiscia, PhD
May 22, 2018
The absolute stereochemistry of chiral carboxylic acids is determined as a di(1-naphthyl)methanol ester derivative. Computational scoring of conformations favoring either P or M helicity… Continue reading Di(1-naphthyl) methanol ester of carboxylic acids for absolute stereochemical determination
Leah Pandiscia, PhD
May 22, 2018
Two rare chiral mixed-valence iron(II,III) coordination networks D-and L-{[FeIIFeIII3O(BTC)3(DEF)3]·0.5H2O}n (D-1 and L-1) (H3BTC = 1,3,5-benzenetricarboxylic acid; DEF = N,N-diethylformamide) have been synthesized without any chiral auxiliary… Continue reading Synthesis, structures and magnetic properties of two chiral mixed-valence iron(II,III) coordination networks
Leah Pandiscia, PhD
May 22, 2018
The thermodynamic properties and phase diagram of the thermal-induced fibrous aggregation of cytochrome c with a simple organic co-solvent, 1,4-dioxane, were determined… Continue reading Thermodynamics of fibrous aggregation of cytochrome cwith 1,4-dioxane
Leah Pandiscia, PhD
May 22, 2018
Eleganstone A (1), a rare diterpene possessing a 5/6/4/5 fused tetracyclic ring skeleton, along with its probable biogenetic precursor (2),… Continue reading New diterpenoids from the marine sponge Dactylospongia elegans
Leah Pandiscia, PhD
May 22, 2018
Förster resonance energy transfer (FRET) studies performed at the single molecule level have unique abilities to probe molecular structure, dynamics,… Continue reading Selective Double-Labeling of Cell-Free Synthesized Proteins for More Accurate smFRET Studies
Leah Pandiscia, PhD
May 22, 2018
In recent years, the potential of α-chymotrypsin (CT) as biocatalysts has expanded new areas of its application ranging from pharmaceutical… Continue reading Influence of cholinium-based ionic liquids on the structural stability and activity of α-chymotrypsin
Leah Pandiscia, PhD
May 22, 2018
Leah Pandiscia, PhD
May 22, 2018
Bacterially-produced recombinant prion protein (rPrP) has traditionally been used for in vitro fibrillation assays and reagent development for prion disease… Continue reading Altered rPrP substrate structures and their influence on real-time quaking induced conversion reactions
Leah Pandiscia, PhD
May 22, 2018
Three pairs of glycosidic 8,4′-oxyneolignane diastereoisomers, named isatioxyneolignosides A−F (1–6), were isolated from an aqueous extract of Isatis indigotica roots. Their structures and absolute… Continue reading 8,4′-Oxyneolignane glucosides from an aqueous extract of “ban lan gen” (Isatis indigotica root) and their absolute configurations
Leah Pandiscia, PhD
May 22, 2018
Leah Pandiscia, PhD
May 22, 2018
Three compounds (1–3) were synthesized, where ethynylferrocene is substituted at different positions of anthracene and anthraquinone, and their biological properties… Continue reading Ferrocene-substituted bis(ethynyl)anthracene compounds as anticancer agents
Leah Pandiscia, PhD
May 22, 2018
Polylactides (PLAs) and polylactones are sustainable and biodegradable polymers with important applications in packaging, horticultural materials, and biomedical fields. The… Continue reading Enzymatic ring-opening polymerization (ROP) of lactides and lactone in ionic liquids and organic solvents: digging the controlling factors
Leah Pandiscia, PhD
May 22, 2018