Leah Pandiscia, PhD
May 22, 2018
Leah Pandiscia, PhD
May 22, 2018
Leah Pandiscia, PhD
May 22, 2018
In the present study, we developed a multi-functional guanine derivative, 8FG, as a G-quadruplex stabilizer, a fluorescent probe for the detection… Continue reading A multi-functional guanine derivative for studying the DNA G-quadruplex structure
Leah Pandiscia, PhD
May 22, 2018
Two novel bisthiourea molecular motor-based catalysts were designed and their dynamic control of activity and stereoselectivity in the Henry reaction… Continue reading Dynamic control over catalytic function using responsive bisthiourea catalysts
Leah Pandiscia, PhD
May 22, 2018
The Gram-negative, rod-shaped bacterium Aeromonas hydrophila has two multifunctional 5′-methylthioadenosine/S-adenosylhomocysteine nucleosidase (MTAN) enzymes, MtaN-1 and MtaN-2, that differ from those in other… Continue reading Structural and Functional Analyses of Periplasmic 5′-Methylthioadenosine/S-Adenosylhomocysteine Nucleosidase from Aeromonas hydrophila
Leah Pandiscia, PhD
May 22, 2018
Ferritin is a bionanomaterial that is widely applied in magnetic resonance imaging, drug delivery systems, biocompatible fluorescence, neutron-capture therapy and… Continue reading Heavy metal detoxification by recombinant ferritin fromApostichopus japonicus
Leah Pandiscia, PhD
May 22, 2018
Using recombinant human wild-type fatty acid binding protein 1 (WT FABP1 T94T) and a variant (FABP1 T94A) protein, fluorescence binding… Continue reading Endocannabinoid Interaction with Human FABP1: Impact of the T94A Variant
Leah Pandiscia, PhD
May 22, 2018
Recombinant silk-elastinlike protein polymers (SELPs) combine the biocompatibility and thermoresponsiveness of human tropoelastin with the strength of silk. Direct control… Continue reading Self-Assembly of Thermoresponsive Recombinant Silk-Elastinlike Nanogels
Leah Pandiscia, PhD
May 22, 2018
latelet-rich plasma (PRP), an autologous blood derived product is a concentrated mix of multiple growth factors and cytokines. Direct injections… Continue reading Sustained release of multicomponent platelet-rich plasma proteins from hydrolytically degradable PEG hydrogels
Leah Pandiscia, PhD
May 22, 2018
Collagen has received considerable attention as a biomaterial for tissue engineering because of its low immunogenicity, controllable biodegradation, and ability… Continue reading Eliminating glutaraldehyde from crosslinked collagen films using supercritical CO2
Leah Pandiscia, PhD
May 22, 2018
U1A protein–stem loop 2 RNA association is a basic step in the assembly of the spliceosomal U1 small nuclear ribonucleoprotein.… Continue reading Role of Electrostatics in Protein–RNA Binding: The Global vs the Local Energy Landscape
Leah Pandiscia, PhD
May 22, 2018
Leah Pandiscia, PhD
May 22, 2018
A first attempt was made to study the fluorescence quenching, structure and unfolding nature of the purified Zingiber montanum (J.Koenig) Link ex… Continue reading Fluorescence quenching, structural and unfolding studies of a purified cysteine protease, ZCPG from Zingiber montanum rhizome
Leah Pandiscia, PhD
May 22, 2018
Recent structural characterizations of the p51 and p66 monomers has established an important starting point for understanding the maturation pathway… Continue reading Identification of drivers for the metamorphic transition of HIV-1 reverse transcriptase
Leah Pandiscia, PhD
May 22, 2018
Two poly(diphenylacetylene) derivatives containing identical chiral pinanyl groups on the para- and meta-positions of the side phenyl ring were prepared, and their… Continue reading Annealing-Induced Circular Dichroism Enhancement in Luminescent Conjugated Polymers with an Intramolecular Stack Structure
Leah Pandiscia, PhD
May 22, 2018
Probing the assembly mechanism, orientation, shape, and structure function relationship of hybrid supramolecular materials is an outstanding challenge. In this… Continue reading Mueller Matrix Fluorescence Spectroscopy for Probing Self-Assembled Peptide-Based Hybrid Supramolecular Structure and Orientation
Leah Pandiscia, PhD
May 22, 2018
Understanding the chemical and physical interactions at the interface of protein surfaces and inorganic crystals has important implications in the… Continue reading Enhancing Enzyme Activity and Immobilization in Nanostructured Inorganic–Enzyme Complexes
Leah Pandiscia, PhD
May 22, 2018
We report interesting hierarchical self-assembled architectures from a designed amphiphilic peptide. The bisignate cotton effects in circular dichroism spectra show… Continue reading Self-assembled chiral nanostructures of amphiphilic peptide: from single molecule to aggregate
Leah Pandiscia, PhD
May 22, 2018
A label -free DNAzyme amplified biosensor is found to be highly selective and sensitive towards fluorescent detection of Pb2+ ions… Continue reading DNAzyme Based Amplified Biosensor on Ultrasensitive Fluorescence Detection of Pb (II) Ions from Aqueous System
Leah Pandiscia, PhD
May 22, 2018