This paper reports the dynamic interfacial behavior of a new interfacially active peptide AM-S, which was designed based on a… Continue reading Interfacial Films Formed by a Biosurfactant Modularized with a Silken Tail
Leah Pandiscia, PhD
May 22, 2018
We propose a method for self-bonding between electrodes using the self-organizational processes of a silica-coated peptide hybrid nanowire. We designed… Continue reading Self-bonding and the electrochemical properties of silica-coated nanowires composed of cobalt-coordinated peptide bundles
Leah Pandiscia, PhD
May 22, 2018
Spider silk proteins comprise a repetitive core domain with polyalanine and glycine/proline-rich stretches flanked by highly conserved nonrepetitive N- and… Continue reading Dimerization of the Conserved N-Terminal Domain of a Spider Silk Protein Controls the Self-Assembly of the Repetitive Core Domain
Leah Pandiscia, PhD
May 22, 2018
Oligomeric amyloid-β 1–42 (Aβ-42) peptides are considered to be the most toxic species connected to the occurrence of Alzheimer’s disease.… Continue reading Glucose directs amyloid-beta into membrane-active oligomers
Leah Pandiscia, PhD
May 22, 2018
Deamidation of an asparagine residue is a spontaneous non-enzymatic post-translational modification that results in the conversion of asparagine into a… Continue reading Role of Site-Specific Asparagine Deamidation in Islet Amyloid Polypeptide Amyloidogenesis: Key Contributions of Residues 14 and 21
Leah Pandiscia, PhD
May 22, 2018
Building proteins into larger, post-translational assemblies in a defined and stable way is still a challenging task. A promising approach… Continue reading Probing the potential of CnaB-type domains for the design of tag/catcher systems
Leah Pandiscia, PhD
May 22, 2018
Cassia buds, the immature fruits of Cinnamomum cassia (Lauraceae), are widely consumed as a food spice, dietary supplements, flavoring agents, and preservatives.… Continue reading Isolation and Characterization of Sesquiterpenoids from Cassia Buds and Their Antimicrobial Activities
Leah Pandiscia, PhD
May 22, 2018
Leah Pandiscia, PhD
May 22, 2018
Supramolecular assemblies were prepared using new amphiphilic dervivatives of N-methyl gylcine and N,N dimethyl-β-alanine. Both N-methylated amino acids were conjugated with 1,4 diamino butane… Continue reading Probing the formation of supramolecular assemblies of amphiphilic N-methyl glycine and N,N dimethyl β-alanine derivatives
Leah Pandiscia, PhD
May 22, 2018
The cobalt–nitrosyl complex [Co(NO)(L3)] is supported by a highly hindered tridentate nitrogen ligand, hydrotris(3-tertiary butyl-5-isopropyl-1-pyrazolyl)borate (denoted as L3−), and shows a linear… Continue reading A cobalt–nitrosyl complex with a hindered hydrotris(pyrazolyl)borate coligand: detailed electronic structure, and reactivity towards dioxygen
Leah Pandiscia, PhD
May 22, 2018
Norsampsone E (1), an unprecedented decarbonyl polycyclic polyprenylated acylphloroglucinol, together with one new and two known analogues (2–4), was isolated… Continue reading Norsampsone E, an unprecedented decarbonyl polycyclic polyprenylated acylphloroglucinol with a homoadamantyl core from Hypericum sampsonii†
Leah Pandiscia, PhD
May 22, 2018
The binding of the common food colorant carmoisine and its inhibitory effect on amyloid fibrillation in lysozyme have been investigated.… Continue reading Interaction and inhibitory influence of the azo dye carmoisine on lysozyme amyloid fibrillogenesis
Leah Pandiscia, PhD
May 22, 2018
Diethylaminoethyl end-modified poly(ethylene glycol) (DEAE-PEG) has been synthesized for the noncovalent PEGylation of proteins. The resulting DEAE-PEG and catalase formed… Continue reading Facile Method of Protein PEGylation by a Mono-Ion Complex
Leah Pandiscia, PhD
May 22, 2018
Leah Pandiscia, PhD
May 22, 2018
Vanillin is a plant secondary metabolite and has numerous beneficial health applications. Divanillin is the homodimer of vanillin and used… Continue reading Induction of axial chirality in divanillin by interaction with bovine serum albumin
Leah Pandiscia, PhD
May 22, 2018
The giant non-fimbrial adhesin SiiE of Salmonella enterica mediates the first contact to the apical site of epithelial cells and enables subsequent… Continue reading Structural and functional dissection reveals distinct roles of Ca2+-binding sites in the giant adhesin SiiE of Salmonella enterica
Leah Pandiscia, PhD
May 22, 2018
Aggregation of Amyloid β (Aβ) in the interneuronal spaces is a major etiopathological factor for onset and progression of Alzheimer’s… Continue reading A Peptide Based Pro-drug Disrupts Alzheimer’s Amyloid into Non-toxic Species and Reduces Aβ Induced Toxicity In Vitro
Leah Pandiscia, PhD
May 22, 2018
Leah Pandiscia, PhD
May 22, 2018
2,2′-Dihydroxybenzil is demonstrated to be a highly diastereoselective stereodynamic receptor for the chiral recognition of amino alcohols. The receptor by… Continue reading Stereoselective Chiral Recognition of Amino Alcohols with 2,2′-Dihydroxybenzil
Leah Pandiscia, PhD
May 22, 2018
Synthesis of terpyridyl based ligands 3-([2,2′:6′,2′′-terpyridin]-4′-yl)-7-methoxy-2-(methylthio)-quinolone, (L1); 3-([2,2′:6′,2′′-terpyridin]-4′-yl)-6-methoxyquinolin-2(1H)-one, (L2); 3-([2,2′-:6′,2′′-terpyridin]-4′-yl)-6-methylquinolin-2(1H)-one (L3) and cyclometalated iridium(III) complexes [[Ir(ppy)2L1]+PF6− (1), [Ir(ppy)2L2]+PF6− (2), [Ir(ppy)2L3]+PF6− (3) (2-phenylpyridine =… Continue reading Influence of substituents on DNA and protein binding of cyclometalated Ir(III) complexes and anticancer activity
Leah Pandiscia, PhD
May 22, 2018