Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
The KALA peptide (WEAKLAKALAKALAKHLAKALAKALKA) is an amphiphilic peptide that forms an α-helical structure at physiological pH. We previously reported that,… Continue reading Identification and evaluation of the minimum unit of a KALA peptide required for gene delivery and immune activation
Leah Pandiscia, PhD
July 28, 2017
An osazone based ligand, hexane-3,4-dione-bis(2′-phenylhydrazone) (LH2), was synthesized by 1:2 M Schiff base condensation of 3,4-hexanedione and phenylhydrazine in dehydrated methanol.… Continue reading Comparative study of an osazone based ligand and its palladium(II) complex with human serum albumin: A spectroscopic, thermodynamic and molecular docking approach
Leah Pandiscia, PhD
July 28, 2017
This is the first study determining the three-dimensional structure of Phl p 5a which reveals a novel mechanism for high… Continue reading Flexible IgE epitope containing domains of Phl p 5 cause high allergenic activity
Leah Pandiscia, PhD
July 28, 2017
Bioorganometallic ferrocene-dipeptide conjugates with the Ala-Pro-cysteamine chain, Fc-L-Ala-L-Pro-NHCH2CH2SH (2) and Fc-L-Ala-D-Pro-NHCH2CH2SH (4) (Fc = ferrocenoyl), were prepared by the reduction of the… Continue reading Controlled self-assembling structures of ferrocene-dipeptide conjugates composed of Ala-Pro-NHCH2CH2SH chain
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
The present study was designed to investigate the chemical constituents of the whole herb of Dichrocephala benthamii. A new megastigmane glucoside… Continue reading Megastigmane glucosides isolated from Dichrocephala benthamii
Leah Pandiscia, PhD
July 28, 2017
Helical peptides were naturally-occurring ordered conformations that mediated various biological functions essential for biotechnology. However, it was difficult for natural… Continue reading pH-controllable cell-penetrating polypeptide possessing cancer targeting
Leah Pandiscia, PhD
July 28, 2017
Self-assemblies of peptide amphiphiles feature their unique structures, high biocompatibility, potential for various applications and have attracted increasing interest in… Continue reading Conformation and Self-Assembly Changes of Isomeric Peptide Amphiphiles Influenced by Switching Tyrosine in the Sequences
Leah Pandiscia, PhD
July 28, 2017
Chiral supramolecules prepared by the additive-driven self-assembly of block copolymers provide a facile method to construct helical nanostructures. In this… Continue reading Spectroscopic investigation on chirality transfer in additive-driven self-assembly of block polymers
Leah Pandiscia, PhD
July 28, 2017
Secretin is a peptide hormone that exerts pleiotropic physiological functions by specifically binding to its cognate membrane-bound receptor. The membrane… Continue reading Identification of a Conformational Heparin-Recognition Motif on the Peptide Hormone Secretin: Key Role for Cell Surface Binding
Leah Pandiscia, PhD
July 28, 2017
Herein, two pairs of chiral 1,8-naphthalimide-based enantiomers incorporating D/L-alanine and pyrene fluorophore moieties were designed and synthesized. The fluorescence emission gradually… Continue reading Circularly polarized luminescence of chiral 1,8-naphthalimide-based pyrene fluorophore induced via supramolecular self-assembly
Leah Pandiscia, PhD
May 24, 2018
Six new compounds including three lignanoids: reevesiacoumarin (1), reevesic acid (2), and reevesilignan (3), and three terpenoids: reevesiterpenol A (4),… Continue reading Bioactive composition of Reevesia formosana root and stem with cytotoxic activity potential†
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
Four new platinum(II) complexes [Pt(dpen)(bpy)](ClO4)2 (1), [Pt(dpen)(phen)](ClO4)2 (2), [Pt(dpen)(dpq)](ClO4)2 (3) and [Pt(dpen)(dppz)](ClO4)2 (4) comprising of different N,N-donor ligands, viz., 2,2′-bipyridine (bpy), 1,l0-phenanthroline (phen), dipyridoquinoxaline (dpq), dipyrido-[3,2-d:2¢,3¢-f–phenazine] (dppz),… Continue reading DNA interaction and cleavage studies of ancillary chiral ligand and N,N-donor ligands coordinated platinum(II) complexes
Leah Pandiscia, PhD
July 28, 2017
There is an urgent need for more efficient treatment for chronic wounds in diabetic patients especially with high risk of… Continue reading Diabetic wound regeneration using heparin-mimetic peptide amphiphile gel in db/db mice
Leah Pandiscia, PhD
July 28, 2017
The ability to tune supramolecular properties such as size, morphology, or metabolic stability is of paramount importance in the field… Continue reading Developing Polyamine-Based Peptide Amphiphiles with Tunable Morphology and Physicochemical Properties
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017